产品名称

英文名称：AZD1981

同义词

AZD1981、802904-66-1、AZD-1981、2-(4-Acetamido-3-((4-chlorophenyl)thio)-2-methyl-1H-indol-1-yl)acetic acid、AZD 1981、UNII-2AD53WQ2CX、2AD53WQ2CX、2-[4-acetamido-3-(4-chlorophenyl)sulfanyl-2-methylindol-1-yl]acetic acid、CHEMBL1914489、1H-Indole-1-acetic acid, 4-(

产品性质

CAS编号：802904-66-1

分子式：C19H17ClN2O3S

分子量：388.87

PubChem编号：11292191

英文别名：AZD1981|802904-66-1|AZD-1981|2-(4-Acetamido-3-((4-chlorophenyl)thio)-2-methyl-1H-indol-1-yl)acetic acid|AZD 1981|UNII-2AD53WQ2CX|2AD53WQ2CX|2-[4-acetamido-3-(4-chlorophenyl)sulfanyl-2-methylindol-1-yl]acetic acid|CHEMBL1914489|1H-Indole-1-acetic acid, 4-(

规格或纯度：≥98%

英文名称：AZD1981

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：AZD1981是一种有效的，选择性CRTh2 (DP2) receptor拮抗剂，IC50为4 nM，比作用于340种其他酶和受体（包括DP1）选择性高1000多倍。AZD1981 is a potent, selective CRTh2 (DP2) receptor antagonist with IC50 of 4 nM, showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1.

ALogP：4

IUPAC Name：2-[4-acetamido-3-(4-chlorophenyl)sulfanyl-2-methylindol-1-yl]acetic acid

INCHI：InChI=1S/C19H17ClN2O3S/c1-11-19(26-14-8-6-13(20)7-9-14)18-15(21-12(2)23)4-3-5-16(18)22(11)10-17(24)25/h3-9H,10H2,1-2H3,(H,21,23)(H,24,25)

InChi Key：JWYIGNODXSRKGP-UHFFFAOYSA-N

Canonical SMILES：CC1=C(C2=C(C=CC=C2N1CC(=O)O)NC(=O)C)SC3=CC=C(C=C3)Cl

Isomeric SMILES：CC1=C(C2=C(C=CC=C2N1CC(=O)O)NC(=O)C)SC3=CC=C(C=C3)Cl

PubChem CID：11292191

ChEMBL Ligand：CHEMBL1914489

CAS Registry No.：802904-66-1

GPCRdb Ligand：AZD1981

溶解性：DMSO 11 mg/mL Water Ethanol

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH302 Harmful if swallowed

预防措施声明：P261,P305+P351+P338

产品包装