产品名称

英文名称：(-)-Scopolamine hydrobromide trihydrate

同义词

SCOPOLAMINE HYDROBROMIDE TRIHYDRATE、Hyoscine hydrobromide trihydrate、Scopolamine hydrobromide、(-)-Scopolamine hydrobromide trihydrate、6533-68-2、Isopto Hyoscine、Hyoscine hydrobromide、Transderm-Scop、Scopolamine HBr trihydrate、Scopolamine hydrobromide hydrat、东莨菪碱氢溴酸盐三水合物

产品性质

CAS编号：6533-68-2

分子式：C17H21NO4·HBr·3H2O

分子量：438.31

Beilstein号：6100670

MDL号：MFCD00012647

PubChem编号：20055509

别名：东莨菪碱氢溴酸盐三水合物

英文别名：SCOPOLAMINE HYDROBROMIDE TRIHYDRATE|Hyoscine hydrobromide trihydrate|Scopolamine hydrobromide|(-)-Scopolamine hydrobromide trihydrate|6533-68-2|Isopto Hyoscine|Hyoscine hydrobromide|Transderm-Scop|Scopolamine HBr trihydrate|Scopolamine hydrobromide hydrat

规格或纯度：98%

英文名称：(-)-Scopolamine hydrobromide trihydrate

应用：毒蕈碱乙酰胆碱(muscarinic acetylcholine)拮抗剂。常用于试验动物中东莨菪碱诱导的记忆缺失。

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：(-)-Scopolamine hydrobromide is the hydrobromide salt of the anticholinergic natural product Scopolamine, isolated from plants of the Solanaceae family. Scopolamine exhibits anticholinergic properties throμgh competitive inhibition of acetylcholine muscarinic receptors with selectivity for mAChR M1. Suppression of the cholinergic response results in decreased activity of the parasympathetic nervous system, widely exploited in studies concerning parasympathetic functioning.毒蕈碱乙酰胆碱(muscarinic acetylcholine)拮抗剂。常用于试验动物中东莨菪碱诱导的记忆缺失。(-)-Scopolamine hydrobromide is the hydrobromide salt of the anticholinergic natural product Scopolamine, isolated from plants of the Solanaceae family. Scopolamine exhibits anticholinergic properties through competitive inhibition of acetylcholine muscarinic receptors with selectivity for mAChR M1. Suppression of the cholinergic response results in decreased activity of the parasympathetic nervous system, widely exploited in studies concerning parasympathetic functioning.A competitive inhibitor of acetylcholine muscarinic receptors.

IUPAC Name：[(1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate;trihydrate;hydrobromide

INCHI：InChI=1S/C17H21NO4.BrH.3H2O/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;;;;/h2-6,11-16,19H,7-9H2,1H3;1H;3*1H2/t11?,12-,13-,14+,15-,16+;;;;/m1..../s1

InChi Key：LACQPOBCQQPVIT-CQPQIMGBSA-N

Canonical SMILES：CN1C2CC(CC1C3C2O3)OC(=O)C(CO)C4=CC=CC=C4.O.O.O.Br

Isomeric SMILES：CN1[C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)[C@H](CO)C4=CC=CC=C4.O.O.O.Br

WGK Germany：1

RTECS：YM4730000

关联CAS：114-49-8

PubChem CID：20055509

溶解性：Soluble in water (666 mg/mL at 25 °C), DMSO (77 mg/mL at 25 °C), and ethanol (18 mg/mL at 25 °C). Insoluble in organic solvents.

象形图：

信号词：Danger

危险声明：H300+H310+H330 Fatal if swallowed, in contact with skin or if inhaled

预防措施声明：P280,P301+P310,P264,P260,P284,P302+P350

个人防护装备：Eyeshields， Faceshields， full-face particle respirator type N100 (US)， Gloves， respirator cartridge type N100 (US)， type P1 (EN143) respirator filter， type P3 (EN 143) respirator cartridges

产品包装