产品名称

英文名称：Monomethyl Fumarate

同义词

Monomethyl fumarate、2756-87-8、4-methoxy-4-oxobut-2-enoic acid、mono-Methyl fumarate、Methyl hydrogen fumarate、Fumaric acid monomethyl ester、(E)-4-methoxy-4-oxobut-2-enoic acid、Bafiertam、(2E)-4-Methoxy-4-oxobut-2-enoic acid、UNII-45IUB1PX8R、45IUB1PX8R、monomet、富马酸单甲酯、反丁烯二酸一甲酯

产品性质

CAS编号：2756-87-8

分子式：C5H6O4

分子量：130.1

MDL号：MFCD00063174

PubChem编号：5369209

别名：富马酸单甲酯|反丁烯二酸一甲酯

英文别名：Monomethyl fumarate|2756-87-8|4-methoxy-4-oxobut-2-enoic acid|mono-Methyl fumarate|Methyl hydrogen fumarate|Fumaric acid monomethyl ester|(E)-4-methoxy-4-oxobut-2-enoic acid|Bafiertam|(2E)-4-Methoxy-4-oxobut-2-enoic acid|UNII-45IUB1PX8R|45IUB1PX8R|monomet

规格或纯度：>98.0%(GC)

英文名称：Monomethyl Fumarate

生化机理：核因子（类胡萝卜素-2）样2（Nrf2）通路激活剂。在GPR109A上也表现出激动剂活性。DMF的主要代谢物。

储存温度：充氩

运输条件：常规运输

产品介绍：mono-Methyl fumarate can be used as a reactant to synthesize · Jumonji C domain-containing histone demethylases (JCHDMs) inhibitor. · (-)-Xylariamide A, a fungal metabolite. · (±)-Methoxyfumimycin ethyl ester, a potential bacterial peptide deformylase inhibitor. It is also a wide spectrum antibacterial agent with a powerful antioxidant activity.mono-Methyl fumarate can be used as a reactant to synthesize · Jumonji C domain-containing histone demethylases (JCHDMs) inhibitor. · (-)-Xylariamide A, a fungal metabolite. · (±)-Methoxyfumimycin ethyl ester, a potential bacterial peptide deformylase inhibitor. It is also a wide spectrum antibacterial agent with a powerful antioxidant activity.

ALogP：0.4

PubChem SID：488195478

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488195478

IUPAC Name：(E)-4-methoxy-4-oxobut-2-enoic acid

INCHI：InChI=1S/C5H6O4/c1-9-5(8)3-2-4(6)7/h2-3H,1H3,(H,6,7)/b3-2+

InChi Key：NKHAVTQWNUWKEO-NSCUHMNNSA-N

Canonical SMILES：COC(=O)C=CC(=O)O

Isomeric SMILES：COC(=O)/C=C/C(=O)O

WGK Germany：3

PubChem CID：5369209

CAS Registry No.：2756-87-8

ChEMBL Ligand：CHEMBL589586

PEP：monomethylfumarate

GPCRdb Ligand：monomethyl fumarate

溶解性：溶于DMSO, 最高浓度 (mg/mL) 13.01, 最高浓度(mM) 100；溶于ethanol, 最高浓度 (mg/mL) 13.01, 最高浓度(mM) 100

熔点：145-149°C

象形图：

信号词：Danger

危险声明：H318 Causes serious eye damage

预防措施声明：P280,P264+P265,P305+P354+P338,P317

个人防护装备：dust mask type N95 (US)， Eyeshields， Gloves

产品包装