产品名称

英文名称：Rotigotine

同义词

(-)-(S)-5,6,7,8-Tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-1-naphthol、Leganto、rotigotinum、DB05271、BDBM50123626、SPM-936、HSDB 8254、ROTIGOTINE (EP MONOGRAPH)、MFCD00870193、ROTIGOTINE [MART.]、R0220、R5F、CS-0376、DTXSID5046772、(2S)-2-[propyl-[2-(2-thienyl)eth、罗替戈汀

产品性质

CAS编号：99755-59-6

分子式：C19H25NOS

分子量：315.47

MDL号：MFCD00906149

PubChem编号：59227

别名：罗替戈汀

英文别名：(-)-(S)-5,6,7,8-Tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-1-naphthol|Leganto|rotigotinum|DB05271|BDBM50123626|SPM-936|HSDB 8254|ROTIGOTINE (EP MONOGRAPH)|MFCD00870193|ROTIGOTINE [MART.]|R0220|R5F|CS-0376|DTXSID5046772|(2S)-2-[propyl-[2-(2-thienyl)eth

规格或纯度：≥98%

英文名称：Rotigotine

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：Rotigotine是一种dopamine receptor的激动剂，用于帕金森氏症和不宁腿综合征的治疗。Rotigotine is a dopamine receptor agonist, used in the treatment of Parkinson's disease and restless legs syndrome.

ALogP：4.9

IUPAC Name：(6S)-6-[propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol

INCHI：InChI=1S/C19H25NOS/c1-2-11-20(12-10-17-6-4-13-22-17)16-8-9-18-15(14-16)5-3-7-19(18)21/h3-7,13,16,21H,2,8-12,14H2,1H3/t16-/m0/s1

InChi Key：KFQYTPMOWPVWEJ-INIZCTEOSA-N

Canonical SMILES：CCCN(CCC1=CC=CS1)C2CCC3=C(C2)C=CC=C3O

Isomeric SMILES：CCCN(CCC1=CC=CS1)[C@H]2CCC3=C(C2)C=CC=C3O

WGK Germany：2

PubChem CID：59227

ChEMBL Ligand：CHEMBL1303

DrugBank Ligand：DB05271

BindingDB Ligand：50054062

Wikipedia：Rotigotine

CAS Registry No.：99755-59-6

PEP：rotigotine

DrugCentral Ligand：2407

GPCRdb Ligand：rotigotine

溶解性：DMSO 63 mg/mL; Water <1 mg/mL; Ethanol 63 mg/mL

敏感性：对热敏感

比旋光度：-42.7° (C=1,MeOH)

熔点：78 °C

象形图：

信号词：Warning

危险声明：H413 May cause long lasting harmful effects to aquatic lifeH302 Harmful if swallowedH336 May cause drowsiness or dizzinessH361 Suspected of damaging fertility or the unborn childH362 May cause harm to breast-fed children

预防措施声明：P261,P273,P280,P405,P501,P264,P260,P271,P270,P304+P340,P403+P233,P330,P263,P203,P301+P317,P318,P319

产品包装