产品名称

英文名称：Ampalex

同义词

Ampalex i(1/4)OECX-516、CHEBI34605、SCHEMBL194605、Ampakine CX516、BDP-12(Ampalex)、EX-A265、Q5014875、9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate)、SCHEMBL36219、cis/trans-Perfluorodecalin、BCP0726000046、CX5、安帕来斯

产品性质

CAS编号：154235-83-3

分子式：C14H15N3O

分子量：241.29

PubChem编号：148184

别名：安帕来斯

英文别名：Ampalex i(1/4)OECX-516|CHEBI34605|SCHEMBL194605|Ampakine CX516|BDP-12(Ampalex)|EX-A265|Q5014875|9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate)|SCHEMBL36219|cis/trans-Perfluorodecalin|BCP0726000046|CX5

规格或纯度：≥95%

英文名称：Ampalex

生化机理：Ampalex (Ampakine CX516; CX516; BDP 12) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI). IC50 value Target AMPA receptor Ampalex ameliorates functional deficits in AMPA receptors in a hippocampal slice model of protein accumulation. Researches sμggest that AMPA receptors may be potential pharmaceutical targets for the treatment of neurodegenerative diseases, and highlights AMPAkines, in particular, as possible therapeutic agents.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：500mg、25mg、100mg卖完停产，不再备货

产品介绍：Ampalex (Ampakine CX516; CX516; BDP 12)是AMPA受体阳性变构调节剂，可作用于阿尔茨海默病，精神分裂等。A series of AMPA modulators for the potential treatment of cognitive diseasesCX516 is a positive allosteric modulator at AMPA receptor that inhibits the deactivation of AMPA receptors. CX-516 is a nootropic and ampakine agentA series of AMPA modulators for the potential treatment of cognitive diseases

PubChem SID：488188210

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488188210

IUPAC Name：piperidin-1-yl(quinoxalin-6-yl)methanone

INCHI：InChI=1S/C14H15N3O/c18-14(17-8-2-1-3-9-17)11-4-5-12-13(10-11)16-7-6-15-12/h4-7,10H,1-3,8-9H2

InChi Key：ANDGGVOPIJEHOF-UHFFFAOYSA-N

Canonical SMILES：C1CCN(CC1)C(=O)C2=CC3=NC=CN=C3C=C2

Isomeric SMILES：C1CCN(CC1)C(=O)C2=CC3=NC=CN=C3C=C2

RTECS：TM2785170

PubChem CID：148184

CAS Registry No.：154235-83-3

ChEMBL Ligand：CHEMBL136800

Wikipedia：CX-516

RCSB PDB Ligand：CX5

溶解性：DMSO

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowed

预防措施声明：P501,P264,P270,P330,P301+P317

产品包装