产品名称

英文名称：Dapivirine (TMC120)

同义词

Dapivirine、244767-67-7、TMC-120、Dapivirine (TMC120)、TMC120、dapivirinum、TMC 120、R 147681、R-147681、4-[[4-(2,4,6-trimethylanilino)pyrimidin-2-yl]amino]benzonitrile、4-({4-[(2,4,6-trimethylphenyl)amino]pyrimidin-2-yl}amino)benzonitrile、Benzonitrile, 4-[[4-[(2,4

产品性质

CAS编号：244767-67-7

分子式：C20H19N5

分子量：329.4

PubChem编号：214347

英文别名：Dapivirine|244767-67-7|TMC-120|Dapivirine (TMC120)|TMC120|dapivirinum|TMC 120|R 147681|R-147681|4-[[4-(2,4,6-trimethylanilino)pyrimidin-2-yl]amino]benzonitrile|4-({4-[(2,4,6-trimethylphenyl)amino]pyrimidin-2-yl}amino)benzonitrile|Benzonitrile, 4-[[4-[(2,4

规格或纯度：≥98%

英文名称：Dapivirine (TMC120)

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：Dapivirine (TMC120)是一种非核苷类抑制剂，作用于HIV逆转录酶，IC50为24 nM，抑制多种不同类型的HIV-1分离株，包括多种耐NNRTI的分离株。Dapivirine (TMC120) is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM, inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates.

ALogP：4.8

IUPAC Name：4-[[4-(2,4,6-trimethylanilino)pyrimidin-2-yl]amino]benzonitrile

INCHI：InChI=1S/C20H19N5/c1-13-10-14(2)19(15(3)11-13)24-18-8-9-22-20(25-18)23-17-6-4-16(12-21)5-7-17/h4-11H,1-3H3,(H2,22,23,24,25)

InChi Key：ILAYIAGXTHKHNT-UHFFFAOYSA-N

Canonical SMILES：CC1=CC(=C(C(=C1)C)NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C

Isomeric SMILES：CC1=CC(=C(C(=C1)C)NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C

PubChem CID：214347

溶解性：DMSO 34 mg/mL Water Ethanol

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowed

预防措施声明：P501,P264,P270,P330,P301+P317

产品包装