产品名称

英文名称：(R,R)-Formoterol

同义词

Formamide, N-(2-hydroxy-5-(1-hydroxy-2-((2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)phenyl)-, (R-(R*,R*))-、FORMOTEROL [WHO-DD]、N-(2-Hydroxy-5-{1-hydroxy-2-[2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenyl)-formamide、eformoterol、FORMOTEROL [HSDB]、福莫特罗

产品性质

CAS编号：67346-49-0

分子式：C19H24N2O4

分子量：344.4

PubChem编号：3083544

别名：福莫特罗

英文别名：Formamide, N-(2-hydroxy-5-(1-hydroxy-2-((2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)phenyl)-, (R-(R*,R*))-|FORMOTEROL [WHO-DD]|N-(2-Hydroxy-5-{1-hydroxy-2-[2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenyl)-formamide|eformoterol|FORMOTEROL [HSDB]

规格或纯度：≥98.0%

英文名称：(R,R)-Formoterol

生化机理：DescriptionIC50 Value N/AFormoterol is a novel highly β2-selective adrenergic agonist and holds promise as a β2-agonist that could impart selective beneficial metabolic effects.in vitro Formoterol restored Dex sensitivity by inhibiting phosphorylation of GR-Ser226 and JNK1[1]. Formoterol (FM), but not SM, partially inhibited H(2) O(2) -induced PI3Kδ-dependent (PKB) phosphorylation. H(2) O(2) decreased SM-induced cAMP production in U937 cells, but did not significantly affect the response to FM [3].in vivo Mice exposed to formoterol for 24 or 72 h exhibited increases in kidney and heart mtDNA copy number, peroxisome proliferator-activated receptor γ coactivator 1α, and multiple genes involved in the mitochondrial electron transport chain (F0 subunit 6 of transmembrane F-type ATP synthase, NADH dehydrogenase subunit 1, NADH dehydrogenase subunit 6, and NADH dehydrogenase [ubiquinone] 1β subcomplex subunit 8) [2

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：Formoterol(Arformoterol)是β2肾上腺素激动剂。Formoterol(Arformoterol) is a novel highly β2-selective adrenergic agonist and holds promise as a β 2-agonist that could impart selective beneficial metabolic effects.

IUPAC Name：N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino]ethyl]phenyl]formamide

INCHI：InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)/t13-,19+/m1/s1

InChi Key：BPZSYCZIITTYBL-YJYMSZOUSA-N

Canonical SMILES：CC(CC1=CC=C(C=C1)OC)NCC(C2=CC(=C(C=C2)O)NC=O)O

Isomeric SMILES：C[C@H](CC1=CC=C(C=C1)OC)NC[C@@H](C2=CC(=C(C=C2)O)NC=O)O

PubChem CID：3083544

Wikipedia：Arformoterol

ChEMBL Ligand：CHEMBL1363

ChEBI：CHEBI408174

CAS Registry No.：67346-49-0

DrugBank Ligand：DB01274

RCSB PDB Ligand：H98

DrugCentral Ligand：4943

GPCRdb Ligand：arformoterol

溶解性：25°C DMSO

象形图：

信号词：Danger

危险声明：H412 Harmful to aquatic life with long lasting effectsH332 Harmful if inhaledH372 Causes damage to organs through prolonged or repeated exposureH370 Causes damage to organsH361 Suspected of damaging fertility or the unborn childH362 May cause harm to breast-fed children

预防措施声明：P261,P273,P280,P321,P405,P501,P264,P260,P271,P270,P304+P340,P263,P203,P318,P317,P308+P316,P319

产品包装