产品名称

英文名称：Omeprazole

同义词

omeprazole、73590-58-6、Losec、Prilosec、Antra、Audazol、Omeprazon、Mopral、Omapren、Parizac、Ceprandal、Dizprazol、Emeproton、Epirazole、Gastrimut、Gastroloc、Inhibitron、Logastric、Peptilcer、Sanamidol、Secrepina、Ulcometion、Belmazol、Dudencer、Gibancer、Indurgan、Inhipump、Mira、5-甲氧基-2-[(4-甲氧基-3,5-二甲基-2-吡啶基)-甲基亚砜]-1H-苯并咪唑、5-甲氧基-2-[(4-甲氧基-3,5-二甲基-2-吡啶基)-甲基亚砜]-3H-苯并咪唑、5-甲氧基-2-[[(4-甲氧基-3,5-二甲基-2-吡啶基)甲基]亚磺酰]-1H-苯并咪唑、洛塞克、亚砜米唑

产品性质

CAS编号：73590-58-6

分子式：C17H19N3O3S

分子量：345.42

MDL号：MFCD00083192

PubChem编号：4594

别名：5-甲氧基-2-[(4-甲氧基-3,5-二甲基-2-吡啶基)-甲基亚砜]-1H-苯并咪唑|5-甲氧基-2-[(4-甲氧基-3,5-二甲基-2-吡啶基)-甲基亚砜]-3H-苯并咪唑|5-甲氧基-2-[[(4-甲氧基-3,5-二甲基-2-吡啶基)甲基]亚磺酰]-1H-苯并咪唑|洛塞克|亚砜米唑

英文别名：omeprazole|73590-58-6|Losec|Prilosec|Antra|Audazol|Omeprazon|Mopral|Omapren|Parizac|Ceprandal|Dizprazol|Emeproton|Epirazole|Gastrimut|Gastroloc|Inhibitron|Logastric|Peptilcer|Sanamidol|Secrepina|Ulcometion|Belmazol|Dudencer|Gibancer|Indurgan|Inhipump|Mira

规格或纯度：98%

英文名称：Omeprazole

生化机理：共价结合质子泵,抑制胃液分泌。选择性，不可逆的H + / K + ATPase质子泵抑制剂（IC 50 = 5.2 µM）。抑制胃酸分泌。抑制细胞色素P450介导的药物代谢。在体外和体内具有活性。细胞和血脑屏障通透。

应用：奥美拉唑是一种质子泵抑制剂，对动物和人胃酸分泌具有很强的和较长时间的抑制作用。

储存温度：2-8°C储存,充氩

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：产品介绍Omeprazole is a benzimidazole derivative, a weak base and is lipophilic in nature. This compound is pH sensitive and does not exists in its original form at low pH.用途Omeprazole has been used as an atypical cytochrome P450 (CYP) 1A2 inducer in Dulbecco′s modified eagle′s medium (serum free) to study the effects of inducers on CYP activities in human hepatocytes and also to compare with other classical aryl hydrocarbon receptor ligands.Product IntroductionOmeprazole is a benzimidazole derivative, a weak base and is lipophilic in nature. This compound is pH sensitive and does not exists in its original form at low pH.ApplicationOmeprazole has been used as an atypical cytochrome P450 (CYP) 1A2 inducer in Dulbecco′s modified eagle′s medium (serum free) to study the effects of inducers on CYP activities in human hepatocytes and also to compare with other classical aryl hydrocarbon receptor ligands.

IUPAC Name：6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole

INCHI：InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)

InChi Key：SUBDBMMJDZJVOS-UHFFFAOYSA-N

Canonical SMILES：CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC

Isomeric SMILES：CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC

WGK Germany：2

RTECS：DD9087000

PubChem CID：4594

Reaxy-Rn：3628192

DrugBank Ligand：DB00338

Wikipedia：Omeprazole

CAS Registry No.：73590-58-6

ChEBI：CHEBI7772

ChEMBL Ligand：CHEMBL1503

PEP：omeprazole

Immunopaedia Search：omeprazole

DrugCentral Ligand：1990

溶解性：Soluble in water (0.5 mg/ml), DMSO (25 mg/ml), and ethanol (4.5 mg/ml).

敏感性：对空气敏感 ；对光线敏感 ；对热敏感

熔点：158-159°C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH412 Harmful to aquatic life with long lasting effectsH302 Harmful if swallowedH317 May cause an allergic skin reactionH312 Harmful in contact with skinH332 Harmful if inhaled

预防措施声明：P261,P305+P351+P338,P273,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P272,P333+P313,P362+P364,P330,P264+P265,P301+P317,P317,P337+P317,P332+P317,P319

Merck Index：6845

个人防护装备：dust mask type N95 (US), Eyeshields, Gloves

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