产品名称

英文名称：ADL5859 HCl

同义词

850173-95-4、ADL5859 HCl、ADL-5859、ADL-5859 Hydrochloride、ADL5859 Hydrochloride、850173-95-4 (ADL 5859 HCl)、N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide hydrochloride、N,N-Diethyl-4-(5-hydroxyspiro[2h-1-benzopyran-2,4'-piperidin]-4-y

产品性质

CAS编号：850173-95-4

分子式：C24H28N2O3·HCl

分子量：428.96

PubChem编号：46931003

英文别名：850173-95-4|ADL5859 HCl|ADL-5859|ADL-5859 Hydrochloride|ADL5859 Hydrochloride|850173-95-4 (ADL 5859 HCl)|N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide hydrochloride|N,N-Diethyl-4-(5-hydroxyspiro[2h-1-benzopyran-2,4'-piperidin]-4-y

规格或纯度：≥98%

英文名称：ADL5859 HCl

生化机理：ADL-5859 (ADL5859) is an δ-opioid receptor agonist (Ki=0.84 nM, EC50=20 nM). ADL-5859 (ADL5859) is an agonist agent that selectively stimulates the δ-opioid receptor with potential application in a wide range of inflammatory, neuropathic and acute pain conditions. In addition, Delta agonists are thoμght to modulate other biological processes that may manifest themselves in disease states or conditions such as overactive bladder and depression.ADL-5859 (ADL5859) is useful for inflammatory, neuropathic and acute pain conditions.

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：ADL5859是δ-阿片受体选择性激动剂，Ki为0.8 nM，对hERG有弱抑制性。A selective receptor agonist for the δ-opioid receptorADL5859 is a δ-opioid receptor agonist with Ki of 0.8 nM, selectivity against opioid receptor κ, μ, and weak inhibitory activity at the hERG channel.A selective receptor agonist for the δ-opioid receptor

IUPAC Name：N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide;hydrochloride

INCHI：InChI=1S/C24H28N2O3.ClH/c1-3-26(4-2)23(28)18-10-8-17(9-11-18)19-16-24(12-14-25-15-13-24)29-21-7-5-6-20(27)22(19)21;/h5-11,16,25,27H,3-4,12-15H2,1-2H3;1H

InChi Key：ZFNLSWREIULTDO-UHFFFAOYSA-N

Canonical SMILES：CCN(CC)C(=O)C1=CC=C(C=C1)C2=CC3(CCNCC3)OC4=CC=CC(=C42)O.Cl

Isomeric SMILES：CCN(CC)C(=O)C1=CC=C(C=C1)C2=CC3(CCNCC3)OC4=CC=CC(=C42)O.Cl

PubChem CID：46931003

溶解性：DMSO 86 mg/mL Water 5 mg/mL Ethanol 1 mg/mL

产品包装