产品名称

英文名称：Rucaparib (AG-014699,PF-01367338)

同义词

Rucaparib phosphate、459868-92-9、AG-014699、PF-01367338、AG014699、AG 014699、Rucaparib (phosphate)、AG-14699、Rucaparib (AG-014699,PF-01367338)、AG-014447、Rucaparib phosphate [USAN]、459868-92-9 (phosphate)、PF01367338、8-Fluoro-2-(4-((methylamino)methyl)phenyl)-4,

产品性质

CAS编号：459868-92-9

分子式：C19H18FN3O·H3PO4

分子量：421.36

PubChem编号：9931953

英文别名：Rucaparib phosphate|459868-92-9|AG-014699|PF-01367338|AG014699|AG 014699|Rucaparib (phosphate)|AG-14699|Rucaparib (AG-014699,PF-01367338)|AG-014447|Rucaparib phosphate [USAN]|459868-92-9 (phosphate)|PF01367338|8-Fluoro-2-(4-((methylamino)methyl)phenyl)-4,

规格或纯度：≥99%

英文名称：Rucaparib (AG-014699,PF-01367338)

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：Rucaparib (AG-014699,PF-01367338)是一种PARP抑制剂，作用于PARP1的Ki为1.4 nM，对其余8个PARP位点也有结合亲和力。Phase 3。Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1, also showing binding affinity to eight other PARP domains. Phase 3.

IUPAC Name：6-fluoro-2-[4-(methylaminomethyl)phenyl]-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-9-one;phosphoric acid

INCHI：InChI=1S/C19H18FN3O.H3O4P/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15;1-5(2,3)4/h2-5,8-9,21,23H,6-7,10H2,1H3,(H,22,24);(H3,1,2,3,4)

InChi Key：FCCGJTKEKXUBFZ-UHFFFAOYSA-N

Canonical SMILES：CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=C3C(=CC(=C4)F)N2.OP(=O)(O)O

Isomeric SMILES：CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=C3C(=CC(=C4)F)N2.OP(=O)(O)O

PubChem CID：9931953

溶解性：DMSO 84 mg/mL Water Ethanol

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH302 Harmful if swallowedH332 Harmful if inhaled

预防措施声明：P305+P351+P338,P280,P310

产品包装