产品名称

英文名称：PIK-293

同义词

PIK-293、900185-01-5、PIK293、2-((4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one、PIK 293、KQDBVHKNIYROHU-UHFFFAOYSA-N、MLS006010992、SCHEMBL1296650、CHEMBL3182327、DTXSID40692887、EX-A880、HMS3655H10、BCP02571、MFCD20272930、s2

产品性质

CAS编号：900185-01-5

分子式：C22H19N7O

分子量：397.43

PubChem编号：53245636

英文别名：PIK-293|900185-01-5|PIK293|2-((4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one|PIK 293|KQDBVHKNIYROHU-UHFFFAOYSA-N|MLS006010992|SCHEMBL1296650|CHEMBL3182327|DTXSID40692887|EX-A880|HMS3655H10|BCP02571|MFCD20272930|s2

规格或纯度：≥97%

英文名称：PIK-293

生化机理：PIK-293 is a PI3-K inhibitor. PIK-293 inhibits the p110α, p110β, p110δ, and p110γ with IC50 of 100 μM, 25 μM, 0.24 μM,and 10 &kkkmu;M. PIK-293 is the parent compound of PIK-294.

应用：A PI3K inhibitor

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：PIK-293 is a PI3K inhibitor, mostly for PI3Kδ with IC50 of 0.24 μM, 500-, 100- and 50-fold less potent to PI3Kα/β/γ, respectively.A PI3K inhibitor

IUPAC Name：2-[(4-aminopyrazolo[3,4-d]pyrimidin-1-yl)methyl]-5-methyl-3-(2-methylphenyl)quinazolin-4-one

INCHI：InChI=1S/C22H19N7O/c1-13-6-3-4-9-17(13)29-18(27-16-8-5-7-14(2)19(16)22(29)30)11-28-21-15(10-26-28)20(23)24-12-25-21/h3-10,12H,11H2,1-2H3,(H2,23,24,25)

InChi Key：KQDBVHKNIYROHU-UHFFFAOYSA-N

Canonical SMILES：CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C5=NC=NC(=C5C=N4)N

Isomeric SMILES：CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C5=NC=NC(=C5C=N4)N

PubChem CID：53245636

溶解性：DMSO 80 mg/mL Water <1 mg/mL Ethanol <1 mg/mL

产品包装