产品名称

英文名称：Olmesartan Medoxomil

同义词

Olmesartan medoxomil、144689-63-4、Benicar、Olmetec、CS-866、Cs 866、Olsertain、UNII-6M97XTV3HD、6M97XTV3HD、NSC-758924、DTXSID9045924、Olmesartan-d4Medoxomil、1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,1'-bipheny、奥美沙坦酯

产品性质

CAS编号：144689-63-4

分子式：C29H30N6O6

分子量：558.59

MDL号：MFCD00944911

PubChem编号：130881

别名：奥美沙坦酯

英文别名：Olmesartan medoxomil|144689-63-4|Benicar|Olmetec|CS-866|Cs 866|Olsertain|UNII-6M97XTV3HD|6M97XTV3HD|NSC-758924|DTXSID9045924|Olmesartan-d4Medoxomil|1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,1'-bipheny

规格或纯度：≥98%

英文名称：Olmesartan Medoxomil

生化机理：Olmesartan Medoxomil is an angiotensin II receptor (AT1) antagonist. This compound also inhibits the negative regulatory feedback on renin secretion. The result of receptor inhibition is vasodilation and a reduction in peripheral resistance.

应用：An angiotensin II receptor antagonist

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：Olmesartan Medoxomil水解产物为Olmesartan，是一种选择性AT1亚型血管紧缩素II受体拮抗剂。An angiotensin II receptor antagonistOlmesartan Medoxomil is a compound which is hydrolyzed to olmesartan that is a selective AT1 subtype angiotensin II receptor antagonist.An angiotensin II receptor antagonist

ALogP：3.8

PubChem SID：488187809

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488187809

IUPAC Name：(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate

INCHI：InChI=1S/C29H30N6O6/c1-5-8-23-30-25(29(3,4)38)24(27(36)39-16-22-17(2)40-28(37)41-22)35(23)15-18-11-13-19(14-12-18)20-9-6-7-10-21(20)26-31-33-34-32-26/h6-7,9-14,38H,5,8,15-16H2,1-4H3,(H,31,32,33,34)

InChi Key：UQGKUQLKSCSZGY-UHFFFAOYSA-N

Canonical SMILES：CCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)OCC5=C(OC(=O)O5)C)C(C)(C)O

Isomeric SMILES：CCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)OCC5=C(OC(=O)O5)C)C(C)(C)O

RTECS：NI4014200

PubChem CID：130881

CAS Registry No.：144689-63-4

ChEMBL Ligand：CHEMBL1200692

DrugBank Ligand：DB00275

Wikipedia：Olmesartan

PEP：olmesartan

Reactome Reaction：R-HSA-9615249

Reactome Drug：R-ALL-9615294

DrugCentral Ligand：1985, 1985

GPCRdb Ligand：olmesartan

溶解性：DMSO 89 mg/mL Water <1 mg/mL Ethanol <1 mg/mL

敏感性：对热敏感

熔点：180-182°C

象形图：

信号词：Danger

危险声明：H319 Causes serious eye irritationH302 Harmful if swallowedH312 Harmful in contact with skinH332 Harmful if inhaledH360 May damage fertility or the unborn child

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P362+P364,P330,P203,P264+P265,P301+P317,P318,P317,P337+P317

Merck Index：6839

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