产品名称

英文名称：SBE 13 hydrochloride

同义词

1052532-15-6、SBE13 hydrochloride、SBE 13 hydrochloride、SBE 13 HCl、SBE13 (Hydrochloride)、SBE-13 HCl、N-(4-((6-chloropyridin-3-yl)methoxy)-3-methoxybenzyl)-2-(3,4-dimethoxyphenyl)ethanamine hydrochloride、MLS000538104、N-[[4-[(6-chloropyridin-3-yl)methoxy]-3-me

产品性质

CAS编号：1052532-15-6

分子式：C24H28Cl2N2O4

分子量：479.4

PubChem编号：11948807

英文别名：1052532-15-6|SBE13 hydrochloride|SBE 13 hydrochloride|SBE 13 HCl|SBE13 (Hydrochloride)|SBE-13 HCl|N-(4-((6-chloropyridin-3-yl)methoxy)-3-methoxybenzyl)-2-(3,4-dimethoxyphenyl)ethanamine hydrochloride|MLS000538104|N-[[4-[(6-chloropyridin-3-yl)methoxy]-3-me

规格或纯度：98% (HPLC)

英文名称：SBE 13 hydrochloride

生化机理：SBE13 is a cell-permeable highly potent polo-like kinase (Plk1) inhibitor that targets the inactive conformation of the kinase. SBE13 does not effect the activity of Plk2, Plk3, Aurora A kinases.

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：产品介绍 SBE13 Hydrochloride 是一种有效的，选择性的 Plk1 抑制剂，IC50 值为 200 pM，对 Plk2 (IC50>66 μM) 或 Plk3 (IC50=875 nM) 的作用较弱。ApplicationSBE 13 hydrochloride may be used in cell signaling studies.

IUPAC Name：N-[[4-[(6-chloropyridin-3-yl)methoxy]-3-methoxyphenyl]methyl]-2-(3,4-dimethoxyphenyl)ethanamine;hydrochloride

INCHI：InChI=1S/C24H27ClN2O4.ClH/c1-28-20-7-4-17(12-22(20)29-2)10-11-26-14-18-5-8-21(23(13-18)30-3)31-16-19-6-9-24(25)27-15-19;/h4-9,12-13,15,26H,10-11,14,16H2,1-3H3;1H

InChi Key：QBGSVDJLQQXEGG-UHFFFAOYSA-N

Canonical SMILES：COC1=C(C=C(C=C1)CCNCC2=CC(=C(C=C2)OCC3=CN=C(C=C3)Cl)OC)OC.Cl

Isomeric SMILES：COC1=C(C=C(C=C1)CCNCC2=CC(=C(C=C2)OCC3=CN=C(C=C3)Cl)OC)OC.Cl

WGK Germany：3

PubChem CID：11948807

溶解性：Soluble in DMSO

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowed

预防措施声明：P305+P351+P338,P280

产品包装