产品名称

英文名称：Amorolfine Hydrochloride

同义词

amorolfine hydrochloride、Amorolfine HCl、78613-38-4、amorolfin、Loceryl、Amorolfine (hydrochloride)、Amorolfine hydrochloride [JAN]、106614-68-0、Ro 14-4767/002、741YH7379H、78613-38-4 (HCl)、(2R,6S)-2,6-dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholi、盐酸阿莫洛芬、阿莫罗芬 盐酸盐

产品性质

CAS编号：78613-38-4

分子式：C21H35NO·HCl

分子量：353.97

MDL号：MFCD00903738

PubChem编号：54259

别名：盐酸阿莫洛芬|阿莫罗芬 盐酸盐

英文别名：amorolfine hydrochloride|Amorolfine HCl|78613-38-4|amorolfin|Loceryl|Amorolfine (hydrochloride)|Amorolfine hydrochloride [JAN]|106614-68-0|Ro 14-4767/002|741YH7379H|78613-38-4 (HCl)|(2R,6S)-2,6-dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholi

规格或纯度：≥98% (HPLC)

英文名称：Amorolfine Hydrochloride

生化机理：Amorolfine is a broad-based antifungal agent with fungicidal effects against most fungi, dermatophytes and yeasts. Amorolfine blocks ergosterol biosynthesis by interfering with delta 14 reduction and the delta 7-8 isomerisation.Broad spectrum antifungal agent. D14 reductase and D7-D8 isomerase inhibitor. Selectively blocks ergosterol biosynthesis. Depletes ergosterol and causes ignosterol to accumulate in the fungal cytoplasmic cell membranes in vivo.

储存温度：2-8°C储存,充氩

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。卖完停产，不再备货

产品介绍：A broad-based antifungal agent which blocks ergosterol biosynthesis.

PubChem SID：488183380

IUPAC Name：(2R,6S)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine;hydrochloride

INCHI：InChI=1S/C21H35NO.ClH/c1-7-21(5,6)20-10-8-19(9-11-20)12-16(2)13-22-14-17(3)23-18(4)15-22;/h8-11,16-18H,7,12-15H2,1-6H3;1H/t16?,17-,18+;

InChi Key：XZKWIPVTHGWDCF-KUZYQSSXSA-N

Canonical SMILES：CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2CC(OC(C2)C)C.Cl

Isomeric SMILES：CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2C[C@H](O[C@H](C2)C)C.Cl

WGK Germany：3

PubChem CID：54259

Reaxy-Rn：9364702

溶解性：Soluble in DMSO (≥5 mg/ml,warmed), water (9l mg/ml), and ethanol (71 mg/ml).

敏感性：易吸湿

熔点：204-208°C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH411 Toxic to aquatic life with long lasting effectsH302 Harmful if swallowed

预防措施声明：P273,P280,P302+P352,P321,P501,P264,P270,P362+P364,P391,P330,P301+P317,P332+P317

产品包装