产品名称

英文名称：ALW-II-41-27

同义词

ALW-II-41-27、1186206-79-0、N-(5-((4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)carbamoyl)-2-methylphenyl)-5-(thiophen-2-yl)nicotinamide、ALW II-41-27、N-[5-[[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-2-methylphenyl

产品性质

CAS编号：1186206-79-0

分子式：C32H32F3N5O2S

分子量：607.69

PubChem编号：42628503

英文别名：ALW-II-41-27|1186206-79-0|N-(5-((4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)carbamoyl)-2-methylphenyl)-5-(thiophen-2-yl)nicotinamide|ALW II-41-27|N-[5-[[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-2-methylphenyl

规格或纯度：≥98%

英文名称：ALW-II-41-27

生化机理：ALW-II-41-27 is a novel Eph receptor tyrosine kinase inhibitor. The Eph family of receptor tyrosine kinases has drawn growing attention due to their role in regulating diverse biological phenomena. The large family of Receptor Tyrosine Kinases, the Ephs, and their binding partners, the ephrins, has been implicated in many cancers of epithelial origin throμgh stimulation of oncogenic transformation, tumor angiogenesis, and promotion of increased cell survival, invasion and migration. They also show promise as both biomarkers of diagnostic and prognostic value and as targeted therapies in cancer.

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：ALW-II-41-27 is a novel Eph receptor tyrosine kinase inhibitor.ALW-II-41-27 is a novel Eph receptor tyrosine kinase inhibitor.

IUPAC Name：N-[5-[[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-2-methylphenyl]-5-thiophen-2-ylpyridine-3-carboxamide

INCHI：InChI=1S/C32H32F3N5O2S/c1-3-39-10-12-40(13-11-39)20-23-8-9-26(17-27(23)32(33,34)35)37-30(41)22-7-6-21(2)28(16-22)38-31(42)25-15-24(18-36-19-25)29-5-4-14-43-29/h4-9,14-19H,3,10-13,20H2,1-2H3,(H,37,41)(H,38,42)

InChi Key：HYWXBDQAYLPMIX-UHFFFAOYSA-N

Canonical SMILES：CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)NC(=O)C4=CN=CC(=C4)C5=CC=CS5)C(F)(F)F

Isomeric SMILES：CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)NC(=O)C4=CN=CC(=C4)C5=CC=CS5)C(F)(F)F

PubChem CID：42628503

溶解性：DMSO

产品包装