产品名称

英文名称：Bradykinin Fragment 1-5

同义词

Bradykinin (1-5)、23815-89-6、Arg-pro-pro-gly-phe、H-Arg-Pro-PRO-Gly-Phe-OH、Thrombostatin、H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT、Arginyl-prolyl-prolyl-glycyl-phenylalanine、CHEMBL1927653、L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanine、L-Phenylalanin

产品性质

CAS编号：23815-89-6

分子式：C27H40N8O6

分子量：572.66

MDL号：MFCD00076260

PubChem编号：3081453

英文别名：Bradykinin (1-5)|23815-89-6|Arg-pro-pro-gly-phe|H-Arg-Pro-PRO-Gly-Phe-OH|Thrombostatin|H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT|Arginyl-prolyl-prolyl-glycyl-phenylalanine|CHEMBL1927653|L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanine|L-Phenylalanin

规格或纯度：≥97% (HPLC)

英文名称：Bradykinin Fragment 1-5

生化机理：The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. It may be used as a marker for BK production in vivo. It is known that an intact Arg residue in the C-terminus is required for biological activities. BK 1-5 is the minimal peptide that inhibited α-thrombin-induced platelet aggregation and secretion and calcium mobilization. It also prevented α-thrombin from cleaving the thrombin receptor peptide, NATLDPRSFLLR, between arginine and serine. Such antithrombin activities of BK 1-5 may contribute to the cardioprotective nature of kinins.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：Amino Acid Sequence Arg-Pro-Pro-Gly-PheAmino Acid Sequence Arg-Pro-Pro-Gly-Phe

IUPAC Name：(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoic acid

INCHI：InChI=1S/C27H40N8O6/c28-18(9-4-12-31-27(29)30)24(38)35-14-6-11-21(35)25(39)34-13-5-10-20(34)23(37)32-16-22(36)33-19(26(40)41)15-17-7-2-1-3-8-17/h1-3,7-8,18-21H,4-6,9-16,28H2,(H,32,37)(H,33,36)(H,40,41)(H4,29,30,31)/t18-,19-,20-,21-/m0/s1

InChi Key：USSUMSBPLJWFSZ-TUFLPTIASA-N

Canonical SMILES：C1CC(N(C1)C(=O)C2CCCN2C(=O)C(CCCN=C(N)N)N)C(=O)NCC(=O)NC(CC3=CC=CC=C3)C(=O)O

Isomeric SMILES：C1C[C@H](N(C1)C(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)N)C(=O)NCC(=O)N[C@@H](CC3=CC=CC=C3)C(=O)O

WGK Germany：3

PubChem CID：3081453

个人防护装备：Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

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