产品名称

英文名称：Deflazacort

同义词

LS-13240、DEFLAZACORT (MART.)、Deflazacort, United States Pharmacopeia (USP) Reference Standard、T70289、Deflazacort (USAN/INN)、DTXSID9020378、InChI=1/C3H5ClO/c1-2-3(4)5/h2H2,1H、Oxazacort、2-((6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-6a,8a,10-trimethyl-4-ox、地夫可特

产品性质

CAS编号：14484-47-0

分子式：C25H31NO6

分子量：441.52

EC号：238-483-7

MDL号：MFCD00866106

PubChem编号：189821

别名：地夫可特

英文别名：LS-13240|DEFLAZACORT (MART.)|Deflazacort, United States Pharmacopeia (USP) Reference Standard|T70289|Deflazacort (USAN/INN)|DTXSID9020378|InChI=1/C3H5ClO/c1-2-3(4)5/h2H2,1H|Oxazacort|2-((6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-6a,8a,10-trimethyl-4-ox

规格或纯度：≥98% (HPLC)

英文名称：Deflazacort

生化机理：Deflazacort is an anti-inflammatory and immunosuppressant glucocorticoid;Deflazacort is derived from prednisolone, a systemic corticosteroid.Potent synthetic glucocorticoid (EC 50 = 13 nM). Prednisolone derivative. Inhibits cutaneous anaphylaxis with little effect on mast cell degranulation Shows anti-inflammatory, antiallergic and immunosuppressant effects in vivo. Orally active.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Deflazacort 是一种糖皮质激素，是一种抗炎剂和免疫抑制剂。A systemic corticosteroid.Deflazacort is a glucocorticoid used as an anti-inflammatory and immunosuppressant.A systemic corticosteroid.

ALogP：2

IUPAC Name：[2-[(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-6,9,13-trimethyl-16-oxo-5-oxa-7-azapentacyclo[10.8.0.02,9.04,8.013,18]icosa-6,14,17-trien-8-yl]-2-oxoethyl] acetate

INCHI：InChI=1S/C25H31NO6/c1-13-26-25(20(30)12-31-14(2)27)21(32-13)10-18-17-6-5-15-9-16(28)7-8-23(15,3)22(17)19(29)11-24(18,25)4/h7-9,17-19,21-22,29H,5-6,10-12H2,1-4H3/t17-,18-,19-,21+,22+,23-,24-,25+/m0/s1

InChi Key：FBHSPRKOSMHSIF-GRMWVWQJSA-N

Canonical SMILES：CC1=NC2(C(O1)CC3C2(CC(C4C3CCC5=CC(=O)C=CC45C)O)C)C(=O)COC(=O)C

Isomeric SMILES：CC1=N[C@@]2([C@H](O1)C[C@@H]3[C@@]2(C[C@@H]([C@H]4[C@H]3CCC5=CC(=O)C=C[C@]45C)O)C)C(=O)COC(=O)C

WGK Germany：3

关联CAS：14484-47-0

PubChem CID：189821

MeSH Entry Terms：Calcort;deflazacort;Dezacor;Emflaza;Zamene

溶解性：Soluble in DMSO (88 mg/ml at 25 °C), methanol, chloroform, water (<1 mg/ml at 25 °C), and ethanol (12 mg/ml at 25 °C).

敏感性：对热敏感

象形图：

信号词：Danger

危险声明：H373 Causes damage to organs through prolonged or repeated exposureH360 May damage fertility or the unborn childH361 Suspected of damaging fertility or the unborn child

预防措施声明：P280,P405,P501,P260,P203,P318,P319

产品包装