产品名称

英文名称：pimavanserin

同义词

Pimavanserin、706779-91-1、ACP-103、1-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea、Pimavanserin [INN]、Pimavanserin free base、UNII-JZ963P0DIK、JZ963P0DIK、Pimavanserin(ACP-103)、Nuplazid (proposed trade name)、CHEBI133017、706779-91-1 (fr

产品性质

CAS编号：706779-91-1

分子式：C25H34FN3O2

分子量：427.6

PubChem编号：10071196

英文别名：Pimavanserin|706779-91-1|ACP-103|1-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea|Pimavanserin [INN]|Pimavanserin free base|UNII-JZ963P0DIK|JZ963P0DIK|Pimavanserin(ACP-103)|Nuplazid (proposed trade name)|CHEBI133017|706779-91-1 (fr

规格或纯度：98%

英文名称：pimavanserin

储存温度：室温

运输条件：常规运输

产品介绍：Product DescribtionPimavanserin(ACP-103) is a potent and selective 5-HT2A receptor inverse agonist with mean pIC50 of with 8.7 in the cell-based functional assay.

IUPAC Name：1-[(4-fluorophenyl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea

INCHI：InChI=1S/C25H34FN3O2/c1-19(2)18-31-24-10-6-20(7-11-24)16-27-25(30)29(23-12-14-28(3)15-13-23)17-21-4-8-22(26)9-5-21/h4-11,19,23H,12-18H2,1-3H3,(H,27,30)

InChi Key：RKEWSXXUOLRFBX-UHFFFAOYSA-N

Canonical SMILES：CC(C)COC1=CC=C(C=C1)CNC(=O)N(CC2=CC=C(C=C2)F)C3CCN(CC3)C

Isomeric SMILES：CC(C)COC1=CC=C(C=C1)CNC(=O)N(CC2=CC=C(C=C2)F)C3CCN(CC3)C

PubChem CID：10071196

ChEMBL Ligand：CHEMBL2111101

CAS Registry No.：706779-91-1

Wikipedia：Pimavanserin

PEP：pimavanserin

DrugCentral Ligand：5142

GPCRdb Ligand：pimavanserin

溶解性：≥21.38 mg/mL in DMSO; insoluble in H2O; ≥54.5 mg/mL in EtOH

象形图：

信号词：Danger

危险声明：H302 Harmful if swallowedH318 Causes serious eye damageH317 May cause an allergic skin reactionH332 Harmful if inhaledH302+H332 Harmful if swallowed or if inhaled

预防措施声明：P261,P280,P302+P352,P321,P501,P264,P271,P270,P304+P340,P272,P333+P313,P362+P364,P330,P264+P265,P301+P317,P305+P354+P338,P317

产品包装