产品名称

英文名称：Alogliptin

同义词

Alogliptin、850649-61-5、alogliptina、(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile、Alogliptin [INN]、UNII-JHC049LO86、alogliptine、alogliptinum、JHC049LO86、SYR322、CHEBI72323、HSDB 8203、2-({6-[(3r)-3-Amino、阿洛利停、阿格列汀

产品性质

CAS编号：850649-61-5

分子式：C18H21N5O2

分子量：339.39

PubChem编号：11450633

别名：阿洛利停|阿格列汀

英文别名：Alogliptin|850649-61-5|alogliptina|(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile|Alogliptin [INN]|UNII-JHC049LO86|alogliptine|alogliptinum|JHC049LO86|SYR322|CHEBI72323|HSDB 8203|2-({6-[(3r)-3-Amino

规格或纯度：≥99%

英文名称：Alogliptin

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：10mg、50mg卖完停产，不再备货

产品介绍：Alogliptin是一种有效的，选择性的DPP-4抑制剂，IC50为<10 nM，比作用于DPP-8和DPP-9选择性高10000倍以上。Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.

PubChem SID：488197519

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488197519

IUPAC Name：2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]benzonitrile

INCHI：InChI=1S/C18H21N5O2/c1-21-17(24)9-16(22-8-4-7-15(20)12-22)23(18(21)25)11-14-6-3-2-5-13(14)10-19/h2-3,5-6,9,15H,4,7-8,11-12,20H2,1H3/t15-/m1/s1

InChi Key：ZSBOMTDTBDDKMP-OAHLLOKOSA-N

Canonical SMILES：CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCCC(C3)N

Isomeric SMILES：CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCC[C@H](C3)N

PubChem CID：11450633

CAS Registry No.：850649-61-5

Wikipedia：Alogliptin

DrugBank Ligand：DB06203

ChEMBL Ligand：CHEMBL376359

RCSB PDB Ligand：T22

PEP：alogliptin

DrugCentral Ligand：4340

溶解性：25°C DMSO 68 mg/mL; Water 2mg/m L; Ethanol <1 mg/mL

象形图：

信号词：Warning

危险声明：H319 Causes serious eye irritationH351 Suspected of causing cancer

预防措施声明：P305+P351+P338,P280,P405,P501,P203,P264+P265,P318,P337+P317

产品包装