产品名称

英文名称：Risperidone

同义词

risperidone、106266-06-2、Risperdal、Risperidal、Rispolept、Risperin、Rispolin、Sequinan、Risperdal Consta、Risperidal M-Tab、Risperidona、Risperidonum、Apexidone、Risperdal M-Tab、Spiron、Risperidonum [Latin]、R 64 766、Belivon、C23H27FN4O2、Perseris、Psychodal、Zophrenal、UN、利培酮、瑞司哌酮

产品性质

CAS编号：106266-06-2

分子式：C23H27FN4O2

分子量：410.48

MDL号：MFCD00274576

PubChem编号：5073

别名：利培酮|瑞司哌酮

英文别名：risperidone|106266-06-2|Risperdal|Risperidal|Rispolept|Risperin|Rispolin|Sequinan|Risperdal Consta|Risperidal M-Tab|Risperidona|Risperidonum|Apexidone|Risperdal M-Tab|Spiron|Risperidonum [Latin]|R 64 766|Belivon|C23H27FN4O2|Perseris|Psychodal|Zophrenal|UN

规格或纯度：≥98%

英文名称：Risperidone

生化机理：Risperidone is an antipsychotic; serotonin-dopamine antagonist.Atypical antipsychotic agent. Potent 5-HT 2A antagonist (K i = 0.4 nM). Also displays high affinity at D 2 receptors (K i = 3.13 nM).

应用：Risperidone has been used · to study its effects on bone formation and differentiation · to investigate the relationship between risperidone (RIS) dosages and RIS plasma levels in autism spectrum disorder (ASD) pediatric patients · to reverse induced schizophrenia-like behavior in mice

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Risperidone is a benzisoxazole derivative. It functions as an antagonist for dopamine D2, histamine H1 and α1 and α2 adrenergic receptors. Risperidone is used to treat schizophrenia, bipolar disorder and autismRisperidone has been used• to study its effects on bone formation and differentiation• to investigate the relationship between risperidone (RIS) dosages and RIS plasma levels in autism spectrum disorder (ASD) pediatric patients• to reverse induced schizophrenia-like behavior in miceRisperidone is a benzisoxazole derivative. It functions as an antagonist for dopamine D2, histamine H1 and α1 and α2 adrenergic receptors. Risperidone is used to treat schizophrenia, bipolar disorder and autismRisperidone has been used• to study its effects on bone formation and differentiation• to investigate the relationship between risperidone (RIS) dosages and RIS plasma levels in autism spectrum disorder (ASD) pediatric patients• to reverse induced schizophrenia-like behavior in mice

ALogP：2.7

IUPAC Name：3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one

INCHI：InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3

InChi Key：RAPZEAPATHNIPO-UHFFFAOYSA-N

Canonical SMILES：CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F

Isomeric SMILES：CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F

WGK Germany：3

RTECS：UV1164800

PubChem CID：5073

UN Number：2811

Packing Group：III

Reaxy-Rn：4891881

DrugBank Ligand：DB00734

CAS Registry No.：106266-06-2

ChEBI：CHEBI8871

Wikipedia：Risperidone

BindingDB Ligand：50001885

ChEMBL Ligand：CHEMBL85

PEP：risperidone

RCSB PDB Ligand：8NU

DrugCentral Ligand：2389

GPCRdb Ligand：risperidone

溶解性：Soluble in DMSO (10 mM), ethanol (10 mM), chloroform, and methanol. Insoluble in water.

熔点：172 °C

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowedH331 Toxic if inhaledH351 Suspected of causing cancerH411 Toxic to aquatic life with long lasting effects

预防措施声明：P261,P273,P280,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P391,P330,P203,P301+P316,P318,P316

Class：6.1

Merck Index：8233

个人防护装备：Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

产品包装