产品名称

英文名称：Licofelone

同义词

ML-3000、2,2-Dimethyl-6-(4-chlorophenyl-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl)acetic acid、2,3-Dihydro-6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-1H-pyrrolizine-5-acetic acid、HMS1923A09、6-(4-Chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizine-5-、利克飞龙

产品性质

CAS编号：156897-06-2

分子式：C23H22ClNO2

分子量：379.88

PubChem编号：133021

别名：利克飞龙

英文别名：ML-3000|2,2-Dimethyl-6-(4-chlorophenyl-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl)acetic acid|2,3-Dihydro-6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-1H-pyrrolizine-5-acetic acid|HMS1923A09|6-(4-Chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizine-5-

规格或纯度：≥98%

英文名称：Licofelone

生化机理：Licofelone is an anti-inflammatory and dual inhibitor of cyclooxygenase and 5-LO(5-lipoxygenase). Licofelone inhibits both Cox-1 and Cox-2.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：Licofelone是COX/LOX的双重抑制剂，用于治疗骨关节炎。An inhibitor of Cox-1, Cox-2, and 5-lipoxygenase.Licofelone is a dual COX/LOX inhibitor being considered as a treatment for osteoarthritisAn inhibitor of Cox-1, Cox-2, and 5-lipoxygenase.

PubChem SID：488187815

IUPAC Name：2-[2-(4-chlorophenyl)-6,6-dimethyl-1-phenyl-5,7-dihydropyrrolizin-3-yl]acetic acid

INCHI：InChI=1S/C23H22ClNO2/c1-23(2)13-19-22(15-6-4-3-5-7-15)21(16-8-10-17(24)11-9-16)18(12-20(26)27)25(19)14-23/h3-11H,12-14H2,1-2H3,(H,26,27)

InChi Key：UAWXGRJVZSAUSZ-UHFFFAOYSA-N

Canonical SMILES：CC1(CC2=C(C(=C(N2C1)CC(=O)O)C3=CC=C(C=C3)Cl)C4=CC=CC=C4)C

Isomeric SMILES：CC1(CC2=C(C(=C(N2C1)CC(=O)O)C3=CC=C(C=C3)Cl)C4=CC=CC=C4)C

PubChem CID：133021

溶解性：Soluble in water (0.5 mg/ml at 25 °C), ethanol (~5 mg/ml), DMSO (20 mg/ml), DMF (20 mg/ml), and methanol.

熔点：165-167°C

象形图：

信号词：Warning

危险声明：H319 Causes serious eye irritationH302 Harmful if swallowed

预防措施声明：P305+P351+P338,P280,P501,P264,P270,P330,P264+P265,P301+P317,P337+P317

产品包装