产品名称

英文名称：Safinamide Mesylate

同义词

Safinamide mesylate、202825-46-5、Safinamide mesilate、(S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanamide methanesulfonate、PNU-151774E、NW-1015、safinamide methanesulfonate、Xadago、PNU 151774E、Safinamide (mesylate)、FCE-28073、NW 1015、Safinamide methansulfon、沙芬酰胺甲磺酸盐

产品性质

CAS编号：202825-46-5

分子式：C17H19FN2O2·CH4O3S

分子量：398.45

MDL号：MFCD15145475

PubChem编号：3038502

别名：沙芬酰胺甲磺酸盐

英文别名：Safinamide mesylate|202825-46-5|Safinamide mesilate|(S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanamide methanesulfonate|PNU-151774E|NW-1015|safinamide methanesulfonate|Xadago|PNU 151774E|Safinamide (mesylate)|FCE-28073|NW 1015|Safinamide methansulfon

规格或纯度：≥98% (HPLC)

英文名称：Safinamide Mesylate

生化机理：Safinamide is a dopamine reuptake inhibitor by being a highly selective inhibitor of MAO-B (IC50 = 98 nM. Additionally, this compound has a high affinity for Na+ channels (IC50 = 8 μM.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：卖完停产，不再备货

产品介绍：Safinamide Mesylate是Safinamide的甲磺酸盐，是一种选择性的且可逆的MAO-B抑制剂，IC50为98 nM，比作用于MAO-A选择性高5918倍。A potent and selective MAO-B inhibitor.Safinamide Mesylate is mesylate salt of Safinamide, selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A.A potent and selective MAO-B inhibitor.

PubChem SID：488194228

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488194228

IUPAC Name：(2S)-2-[[4-[(3-fluorophenyl)methoxy]phenyl]methylamino]propanamide;methanesulfonic acid

INCHI：InChI=1S/C17H19FN2O2.CH4O3S/c1-12(17(19)21)20-10-13-5-7-16(8-6-13)22-11-14-3-2-4-15(18)9-14;1-5(2,3)4/h2-9,12,20H,10-11H2,1H3,(H2,19,21);1H3,(H,2,3,4)/t12-;/m0./s1

InChi Key：YKOCHIUQOBQIAC-YDALLXLXSA-N

Canonical SMILES：CC(C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F.CS(=O)(=O)O

Isomeric SMILES：C[C@@H](C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F.CS(=O)(=O)O

WGK Germany：3

PubChem CID：3038502

溶解性：DMSO 80 mg/mL Water 80 mg/mL Ethanol 13 mg/mL

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowedH318 Causes serious eye damageH400 Very toxic to aquatic life

预防措施声明：P305+P351+P338,P273,P280,P301+P310

产品包装