产品名称

英文名称：iCRT-14

同义词

iCRT 14、677331-12-3、iCRT14、iCRT-14、(5Z)-5-[(2,5-dimethyl-1-pyridin-3-ylpyrrol-3-yl)methylidene]-3-phenyl-1,3-thiazolidine-2,4-dione、CHEMBL3589010、(5Z)-5-{[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene}-3-phenyl-1,3-thiazolidine-2,4-dione、(5Z)-5-{[

产品性质

CAS编号：677331-12-3

分子式：C21H17N3O2S

分子量：375.44

MDL号：MFCD04366833

PubChem编号：5967294

英文别名：iCRT 14|677331-12-3|iCRT14|iCRT-14|(5Z)-5-[(2,5-dimethyl-1-pyridin-3-ylpyrrol-3-yl)methylidene]-3-phenyl-1,3-thiazolidine-2,4-dione|CHEMBL3589010|(5Z)-5-{[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene}-3-phenyl-1,3-thiazolidine-2,4-dione|(5Z)-5-{[

规格或纯度：≥98% (HPLC)

英文名称：iCRT-14

生化机理：iCRT 14 is a potent inhibitor of β-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). iCRT 14 may also directly influence the interaction between β-catenin and TCF4.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：卖完停产，不再备货

产品介绍：iCRT-14是β-catenin应答转录（CRT）抑制剂，在wnt通路实验中IC50为40.3 nMA potent beta-catenin inhibitoriCRT-14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity).A potent beta-catenin inhibitor

IUPAC Name：(5Z)-5-[(2,5-dimethyl-1-pyridin-3-ylpyrrol-3-yl)methylidene]-3-phenyl-1,3-thiazolidine-2,4-dione

INCHI：InChI=1S/C21H17N3O2S/c1-14-11-16(15(2)23(14)18-9-6-10-22-13-18)12-19-20(25)24(21(26)27-19)17-7-4-3-5-8-17/h3-13H,1-2H3/b19-12-

InChi Key：NCSHZXNGQYSKLR-UNOMPAQXSA-N

Canonical SMILES：CC1=CC(=C(N1C2=CN=CC=C2)C)C=C3C(=O)N(C(=O)S3)C4=CC=CC=C4

Isomeric SMILES：CC1=CC(=C(N1C2=CN=CC=C2)C)/C=C\3/C(=O)N(C(=O)S3)C4=CC=CC=C4

WGK Germany：3

PubChem CID：5967294

溶解性：Soluble in DMSO (75 mM), and ethanol (5 mM).

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowed

预防措施声明：P501,P264,P270,P330,P301+P317

产品包装