产品名称

英文名称：Asunaprevir

同义词

BMS650032、HY-14434、D10093、N-(Tert-Butoxycarbonyl)-3-Methyl-L-Valyl-(4r)-4-[(7-Chloro-4-Methoxyisoquinolin-1-Yl)oxy]-N-{(1r,2s)-1-[(Cyclopropylsulfonyl)carbamoyl]-2-Ethenylcyclopropyl}-L-Prolinamide、compound 24 [PMID 24564672]、UNII-S9X0KRJ00S、CS-0151880、E、阿那匹韦

产品性质

CAS编号：630420-16-5

分子式：C35H46ClN5O9S

分子量：748.29

PubChem编号：16076883

别名：阿那匹韦

英文别名：BMS650032|HY-14434|D10093|N-(Tert-Butoxycarbonyl)-3-Methyl-L-Valyl-(4r)-4-[(7-Chloro-4-Methoxyisoquinolin-1-Yl)oxy]-N-{(1r,2s)-1-[(Cyclopropylsulfonyl)carbamoyl]-2-Ethenylcyclopropyl}-L-Prolinamide|compound 24 [PMID 24564672]|UNII-S9X0KRJ00S|CS-0151880|E

规格或纯度：≥98%

英文名称：Asunaprevir

生化机理：Asunaprevir is an inhibitor of the viral enzyme serine protease HCV NS3.

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

产品介绍：Asunaprevir (BMS-650032) is a potent hepatitis C virus (HCV) NS3 protease inhibitor.An inhibitor of the viral enzyme serine protease HCV NS3.Asunaprevir (BMS-650032) is a potent hepatitis C virus (HCV) NS3 protease inhibitor.An inhibitor of the viral enzyme serine protease HCV NS3.

ALogP：4.9

IUPAC Name：tert-butyl N-[(2S)-1-[(2S,4R)-4-(7-chloro-4-methoxyisoquinolin-1-yl)oxy-2-[[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]carbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate

INCHI：InChI=1S/C35H46ClN5O9S/c1-9-19-16-35(19,31(44)40-51(46,47)22-11-12-22)39-28(42)25-15-21(49-29-24-14-20(36)10-13-23(24)26(48-8)17-37-29)18-41(25)30(43)27(33(2,3)4)38-32(45)50-34(5,6)7/h9-10,13-14,17,19,21-22,25,27H,1,11-12,15-16,18H2,2-8H3,(H,38,45)(H,39,42)(H,40,44)/t19-,21-,25+,27-,35-/m1/s1

InChi Key：XRWSZZJLZRKHHD-WVWIJVSJSA-N

Canonical SMILES：CC(C)(C)C(C(=O)N1CC(CC1C(=O)NC2(CC2C=C)C(=O)NS(=O)(=O)C3CC3)OC4=NC=C(C5=C4C=C(C=C5)Cl)OC)NC(=O)OC(C)(C)C

Isomeric SMILES：CC(C)(C)[C@@H](C(=O)N1C[C@@H](C[C@H]1C(=O)N[C@@]2(C[C@H]2C=C)C(=O)NS(=O)(=O)C3CC3)OC4=NC=C(C5=C4C=C(C=C5)Cl)OC)NC(=O)OC(C)(C)C

PubChem CID：16076883

CAS Registry No.：630420-16-5

ChEMBL Ligand：CHEMBL2105735

RCSB PDB Ligand：2R9

DrugBank Ligand：DB11586

DrugCentral Ligand：4889

溶解性：Soluble in DMSO.

象形图：

信号词：Warning

危险声明：H373 Causes damage to organs through prolonged or repeated exposure

预防措施声明：P501,P260,P319

产品包装