产品名称

英文名称：Elagolix sodium salt

同义词

Elagolix sodium、Elagolix sodium salt、832720-36-2、Orlissa、Elagolix sodium [USAN]、NBI-56418 NA、UNII-5948VUI423、NBI-56418-NA、5948VUI423、832720-36-2 (sodium)、ORIAHNN COMPONENT ELAGOLIX SODIUM、ELAGOLIX SODIUM COMPONENT OF ORIAHNN、Elagolix sodium (USAN)、sodium

产品性质

CAS编号：832720-36-2

分子式：C32H29F5N3NaO5

分子量：653.582

PubChem编号：24785956

英文别名：Elagolix sodium|Elagolix sodium salt|832720-36-2|Orlissa|Elagolix sodium [USAN]|NBI-56418 NA|UNII-5948VUI423|NBI-56418-NA|5948VUI423|832720-36-2 (sodium)|ORIAHNN COMPONENT ELAGOLIX SODIUM|ELAGOLIX SODIUM COMPONENT OF ORIAHNN|Elagolix sodium (USAN)|sodium

规格或纯度：97%

英文名称：Elagolix sodium salt

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

产品介绍：产品介绍Elagolix Soidum (NBI-56418, ABT-620) 是一种有效的、选择性的、具有口服活性的促性腺激素释放激素受体GnRHR非肽段拮抗剂，Kd值为54 pM。浓度为10 μM时，对离子通道、酶和转运体没有显著的活性作用(inhibition <50%)。Product DescriptionElagolix Soidum (NBI-56418, ABT-620) is a potent, selective, orally active, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with Kd value of 54 pM. Concentration at 10 μM shows no significant activity on ion channels, enzymes, and transporters (inhibition <50%).

IUPAC Name：sodium;4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-dioxopyrimidin-1-yl]-1-phenylethyl]amino]butanoate

INCHI：InChI=1S/C32H30F5N3O5.Na/c1-19-28(21-11-6-14-26(45-2)29(21)34)30(43)40(18-25(20-9-4-3-5-10-20)38-16-8-15-27(41)42)31(44)39(19)17-22-23(32(35,36)37)12-7-13-24(22)33;/h3-7,9-14,25,38H,8,15-18H2,1-2H3,(H,41,42);/q;+1/p-1/t25-;/m0./s1

InChi Key：DQYGXRQUFSRDCH-UQIIZPHYSA-M

Canonical SMILES：CC1=C(C(=O)N(C(=O)N1CC2=C(C=CC=C2F)C(F)(F)F)CC(C3=CC=CC=C3)NCCCC(=O)[O-])C4=C(C(=CC=C4)OC)F.[Na+]

Isomeric SMILES：CC1=C(C(=O)N(C(=O)N1CC2=C(C=CC=C2F)C(F)(F)F)C[C@@H](C3=CC=CC=C3)NCCCC(=O)[O-])C4=C(C(=CC=C4)OC)F.[Na+]

PubChem CID：24785956

溶解性：DMSO (Slightly), Methanol (Slightly) ， >188°C (dec.)

敏感性：对湿度敏感

象形图：

信号词：Danger

危险声明：H319 Causes serious eye irritationH360 May damage fertility or the unborn childH304 May be fatal if swallowed and enters airwaysH361 Suspected of damaging fertility or the unborn child

预防措施声明：P305+P351+P338,P280,P405,P501,P331,P203,P264+P265,P301+P316,P318,P337+P317

产品包装