产品名称

英文名称：2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

同义词

2-Bromo-1-(3,3-dinitroazetidin-1-yl)ethanone 、 RRX-001 、 2-BROMO-1-(3,3-DINITROAZETIDIN-1-YL)ETHAN-1-ONE ABDNAZ

产品性质

CAS编号：925206-65-1

分子式：C5H6BrN3O5

分子量：268.02

PubChem编号：15950826

英文别名：2-Bromo-1-(3,3-dinitroazetidin-1-yl)ethanone | RRX-001 | 2-BROMO-1-(3,3-DINITROAZETIDIN-1-YL)ETHAN-1-ONE ABDNAZ

规格或纯度：97%

英文名称：2-bromo-1-(3,3-dinitroazetidin-1-yl)ethan-1-one

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：产品介绍RRx-001 是一种低氧选择性的表观遗传因子，被用作放射或化疗敏感剂，能诱发凋亡，克服骨髓瘤的耐药性。RRx-001 具有有效的抗癌活性且毒性极低。RRx-001是一个免疫检查点的抑制剂，可下调 CD47 和SIRP-α。RRx-001是G6PD的有效抑制剂，具有较强的抗疟活性。Product DescribtionRRx-001, a hypoxia-selective epigenetic agent and studied as a radio- and chem-sensitizer, triggers apoptosis and overcomes drug resistance in myeloma. RRx-001 exhibits potent anti-tumor activity with minimal toxicity. RRx-001 is a dual small molecule checkpoint inhibitor by downregulating CD47 and SIRP-α. RRx-001 is a potent inhibitor of G6PD and shows potent antimalarial activity.

IUPAC Name：2-bromo-1-(3,3-dinitroazetidin-1-yl)ethanone

INCHI：InChI=1S/C5H6BrN3O5/c6-1-4(10)7-2-5(3-7,8(11)12)9(13)14/h1-3H2

InChi Key：JODKFOVZURLVTG-UHFFFAOYSA-N

Canonical SMILES：C1C(CN1C(=O)CBr)([N+](=O)[O-])[N+](=O)[O-]

Isomeric SMILES：C1C(CN1C(=O)CBr)([N+](=O)[O-])[N+](=O)[O-]

PubChem CID：15950826

产品包装