产品名称

英文名称：MLN120B

同义词

MLN120B、783348-36-7、MLN-120B、ml120b、ML-120B、N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylnicotinamide、GD8S432HM5、UNII-GD8S432HM5、CHEMBL608154、3-Pyridinecarboxamide, N-(6-chloro-7-methoxy-9H-pyrido(3,4-b)indol-8-yl)-2-methyl-、N-(6-Chloro-7-met

产品性质

CAS编号：783348-36-7

分子式：C19H15ClN4O2

分子量：366.8

PubChem编号：9929127

英文别名：MLN120B|783348-36-7|MLN-120B|ml120b|ML-120B|N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylnicotinamide|GD8S432HM5|UNII-GD8S432HM5|CHEMBL608154|3-Pyridinecarboxamide, N-(6-chloro-7-methoxy-9H-pyrido(3,4-b)indol-8-yl)-2-methyl-|N-(6-Chloro-7-met

规格或纯度：≥98%

英文名称：MLN120B

生化机理：ML120B is a potent inhibitor of IKK-2 (IC50 = 60 nM). ML120B is orally bioavailable, and inhibits paw swelling, bone and cartilage degradation, and weight loss in rat adjuvant-induced arthritis.

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：MLN120B是IKKβ抑制剂。MLN120B is a potent and effective IKKbeta inhibitor.

IUPAC Name：N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylpyridine-3-carboxamide

INCHI：InChI=1S/C19H15ClN4O2/c1-10-11(4-3-6-22-10)19(25)24-17-16-13(8-14(20)18(17)26-2)12-5-7-21-9-15(12)23-16/h3-9,23H,1-2H3,(H,24,25)

InChi Key：ZNOLRTPMNMPLHY-UHFFFAOYSA-N

Canonical SMILES：CC1=C(C=CC=N1)C(=O)NC2=C3C(=CC(=C2OC)Cl)C4=C(N3)C=NC=C4

Isomeric SMILES：CC1=C(C=CC=N1)C(=O)NC2=C3C(=CC(=C2OC)Cl)C4=C(N3)C=NC=C4

PubChem CID：9929127

CAS Registry No.：783348-36-7

DiscoveRx TREEspot：MLN-120B|

ChEMBL Ligand：CHEMBL608154

溶解性：insoluble in H2O; ≥13.2 mg/mL in DMSO; ≥8.53 mg/mL in EtOH with gentle warming and ultrasonic

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowed

预防措施声明：P501,P264,P270,P330,P301+P317

产品包装