产品名称

英文名称：lumateperone Tosylate

同义词

lumateperone Tosylate、1187020-80-9、lumateperone (Tosylate)、ITI-007 tosylate、ITI 007、UNII-JIE88N006O、JIE88N006O、ITI007、Lumateperone tosylate [USAN]、1-(4-fluorophenyl)-4-[(10R,15S)-4-methyl-1,4,12-triazatetracyclo[7.6.1.05,16.010,15]hexadeca-5,7,9(16)-trien

产品性质

CAS编号：1187020-80-9

分子式：C24H28FN3O.C7H8O3S

分子量：565.7

PubChem编号：44241743

英文别名：lumateperone Tosylate|1187020-80-9|lumateperone (Tosylate)|ITI-007 tosylate|ITI 007|UNII-JIE88N006O|JIE88N006O|ITI007|Lumateperone tosylate [USAN]|1-(4-fluorophenyl)-4-[(10R,15S)-4-methyl-1,4,12-triazatetracyclo[7.6.1.05,16.010,15]hexadeca-5,7,9(16)-trien

规格或纯度：98%

英文名称：lumateperone Tosylate

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：Lumateperone甲苯磺酸盐是5-HT 2A受体拮抗剂 (KI= 0.54 nM), 突触前D2受体的部分激动剂和突触后D2受体的拮抗剂 (KI= 32 nM)。Lumateperone Tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a SERT blocker (Ki = 61 nM).

IUPAC Name：1-(4-fluorophenyl)-4-[(10R,15S)-4-methyl-1,4,12-triazatetracyclo[7.6.1.05,16.010,15]hexadeca-5,7,9(16)-trien-12-yl]butan-1-one;4-methylbenzenesulfonic acid

INCHI：InChI=1S/C24H28FN3O.C7H8O3S/c1-26-14-15-28-21-11-13-27(16-20(21)19-4-2-5-22(26)24(19)28)12-3-6-23(29)17-7-9-18(25)10-8-17;1-6-2-4-7(5-3-6)11(8,9)10/h2,4-5,7-10,20-21H,3,6,11-16H2,1H3;2-5H,1H3,(H,8,9,10)/t20-,21-;/m0./s1

InChi Key：LHAPOGAFBLSJJQ-GUTACTQSSA-N

Canonical SMILES：CC1=CC=C(C=C1)S(=O)(=O)O.CN1CCN2C3CCN(CC3C4=C2C1=CC=C4)CCCC(=O)C5=CC=C(C=C5)F

Isomeric SMILES：CC1=CC=C(C=C1)S(=O)(=O)O.CN1CCN2[C@H]3CCN(C[C@H]3C4=C2C1=CC=C4)CCCC(=O)C5=CC=C(C=C5)F

PubChem CID：44241743

溶解性：DMSO ≥ 250 mg/mL (441.93 mM)

产品包装