产品名称

英文名称：CEP-40783

同义词

CEP-40783、1437321-24-8、RXDX-106、CEP40783、N-[4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide、N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-diox

产品性质

CAS编号：1437321-24-8

分子式：C31H26F2N4O6

分子量：588.6

PubChem编号：71576419

英文别名：CEP-40783|1437321-24-8|RXDX-106|CEP40783|N-[4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide|N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-diox

规格或纯度：98%

英文名称：CEP-40783

储存温度：室温

运输条件：常规运输

产品介绍：产品介绍RXDX-106 (CEP-40783)是一种有效的、选择性的TAM(TYRO3, AXL, MER)/Met (c-Met)抑制剂，在肽段磷酸化实验中具有较低的纳摩尔级别生化活性；在体外激酶结合试验中具有慢速的解离率（T1/2 >120 min）

PubChem SID：488202264

IUPAC Name：N-[4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide

INCHI：InChI=1S/C31H26F2N4O6/c1-17(2)36-16-22(30(39)37(31(36)40)20-8-5-18(32)6-9-20)29(38)35-19-7-10-26(23(33)13-19)43-25-11-12-34-24-15-28(42-4)27(41-3)14-21(24)25/h5-17H,1-4H3,(H,35,38)

InChi Key：FKCWHHYUMFGOPY-UHFFFAOYSA-N

Canonical SMILES：CC(C)N1C=C(C(=O)N(C1=O)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C5C=C(C(=CC5=NC=C4)OC)OC)F

Isomeric SMILES：CC(C)N1C=C(C(=O)N(C1=O)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C5C=C(C(=CC5=NC=C4)OC)OC)F

PubChem CID：71576419

产品包装