产品名称

英文名称：Naltrexone

同义词

BDBM60212、DTXCID2026313、HY-76711、NCGC00024427-03、AR-270/43507956、Naltrexonum、Prestwick1_000116、beta-naftyloamina、Tox21_112007、(4R,4As,7aR)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one、17-(Cy、纳曲酮

产品性质

CAS编号：16590-41-3

分子式：C20H23NO4

分子量：341.4

MDL号：MFCD00242996

PubChem编号：5360515

别名：纳曲酮

英文别名：BDBM60212|DTXCID2026313|HY-76711|NCGC00024427-03|AR-270/43507956|Naltrexonum|Prestwick1_000116|beta-naftyloamina|Tox21_112007|(4R,4As,7aR)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one|17-(Cy

规格或纯度：98%

英文名称：Naltrexone

生化机理：Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. Naltrexone is competitive antagonist for μ, κ, δ, and σ-opioid receptors, Naltrexone has greater oral efficacy and longer duration of action than naloxone.

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

产品介绍：ApplicationNaltrexone is an opioid antagonist shown to reduce the occurrence of addictive behaviours such as eating, smoking and drinking excessively. in addition to curbing drug use， it has recently been used in flavor avoidance studies.

ALogP：1.9

IUPAC Name：(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one

INCHI：InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1

InChi Key：DQCKKXVULJGBQN-XFWGSAIBSA-N

Canonical SMILES：C1CC1CN2CCC34C5C(=O)CCC3(C2CC6=C4C(=C(C=C6)O)O5)O

Isomeric SMILES：C1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O

WGK Germany：1

PubChem CID：5360515

Wikipedia：Naltrexone

DrugBank Ligand：DB00704

CAS Registry No.：16590-41-3

ChEMBL Ligand：CHEMBL19019

ChEBI：CHEBI7465

PEP：naltrexone

DrugCentral Ligand：1765

GPCRdb Ligand：naltrexone

溶解性：Chloroform (Slightly), Methanol (Slightly)

熔点：168-172°C

象形图：

信号词：Danger

危险声明：H341 Suspected of causing genetic defectsH302 Harmful if swallowedH317 May cause an allergic skin reactionH334 May cause allergy or asthma symptoms or breathing difficulties if inhaledH312 Harmful in contact with skinH400 Very toxic to aquatic lifeH332 Harmful if inhaled

预防措施声明：P261,P273,P280,P302+P352,P321,P405,P501,P264,P284,P281,P271,P270,P304+P340,P272,P333+P313,P362+P364,P391,P330,P203,P301+P317,P318,P317,P342+P316

产品包装