产品名称

英文名称：N-Benzyl-p-Toluenesulfonamide

同义词

N-Benzyl-p-toluenesulfonamide、1576-37-0、N-Tosylbenzylamine、N-Benzyl-4-methylbenzenesulfonamide、N-Benzyl-4-methyl-benzenesulfonamide、N-Benzyl-p-toluenesulphonamide、p-Toluenesulfonamide, N-benzyl-、Benzenesulfonamide, 4-methyl-N-(phenylmethyl)-、N-benzyl-4-me、N-苄基-对甲苯磺酸胺、N-甲苯磺酸苄胺、N-苄基-p-甲苯磺酰亚胺

产品性质

CAS编号：1576-37-0

分子式：C14H15NO2S

分子量：261.34

Beilstein号：12(3)2328

MDL号：MFCD00159328

PubChem编号：95801

别名：N-苄基-对甲苯磺酸胺|N-甲苯磺酸苄胺|N-苄基-p-甲苯磺酰亚胺

英文别名：N-Benzyl-p-toluenesulfonamide|1576-37-0|N-Tosylbenzylamine|N-Benzyl-4-methylbenzenesulfonamide|N-Benzyl-4-methyl-benzenesulfonamide|N-Benzyl-p-toluenesulphonamide|p-Toluenesulfonamide, N-benzyl-|Benzenesulfonamide, 4-methyl-N-(phenylmethyl)-|N-benzyl-4-me

规格或纯度：≥98.0%(HPLC)

英文名称：N-Benzyl-p-Toluenesulfonamide

生化机理：Ca 2+刺激的肌球蛋白S1 ATPase的选择性抑制剂（IC 50 =〜5 µM）。可逆地阻止滑行运动并减弱肌球蛋白与F-肌动蛋白的相互作用。Target IC50 ~5 µM against Ca2+-stimulated myosin S1 ATPase Product does not compete with ATP. Primary Target Ca2+-stimulated myosin S1 ATPase Cell permeable no Reversible yes

储存温度：避光,-20°C储存,充氩

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：product descriptionAn aryl sulphonamide that acts as a potent inhibitor of Ca2+-stimulated myosin S1 actin-stimulated ATPase activity (IC50 = ~5 µM). Also blocks actin-stimulated ATPase activity with similar potency (IC50 = 5 µM). Reversibly blocks gliding motility of skeletal muscle myosin (IC50<2 µM). Less effective in suppressing contraction in rat myocardial and rabbit slow twitch muscle compared to skeletal muscle. Does not inhibit platelet myosin II.A potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 = ~ 5 µM) and reversibly blocks the gliding motility. It also weakens myosin’s interaction with F-actin. Much less effective in suppressing contraction in rat myocardial or rabbit slow twitch muscle and has no effect on platelet myosin II.

IUPAC Name：N-benzyl-4-methylbenzenesulfonamide

INCHI：InChI=1S/C14H15NO2S/c1-12-7-9-14(10-8-12)18(16,17)15-11-13-5-3-2-4-6-13/h2-10,15H,11H2,1H3

InChi Key：WTHKAJZQYNKTCJ-UHFFFAOYSA-N

Canonical SMILES：CC1=CC=C(C=C1)S(=O)(=O)NCC2=CC=CC=C2

Isomeric SMILES：CC1=CC=C(C=C1)S(=O)(=O)NCC2=CC=CC=C2

RTECS：XT5490000

PubChem CID：95801

Reaxy-Rn：2217277

溶解性：Chloroform (Slightly), Dichloromethane, Ethyl Acetate (Slightly)

敏感性：对光线敏感

熔点：115 °C

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowed

预防措施声明：P321,P405,P501,P264,P270,P330,P301+P316

产品包装