产品名称

英文名称：Rivastigmine Tartrate

同义词

Rivastigmine tartrate、129101-54-8、Rivastigmine Hydrogen Tartrate、SDZ-ENA 713、Rivastigmine bitartrate、ENA 713、Rivastigmine hydrogentartrate、Rivastigmine (tartrate)、(S)-3-(1-(Dimethylamino)ethyl)phenyl ethyl(methyl)carbamate (2R,3R)-2,3-dihydroxysuccinate、U、L-酒石酸卡巴拉汀

产品性质

CAS编号：129101-54-8

分子式：C14H22N2O2 · C4H6O6

分子量：400.42

PubChem编号：6918078

别名：L-酒石酸卡巴拉汀

英文别名：Rivastigmine tartrate|129101-54-8|Rivastigmine Hydrogen Tartrate|SDZ-ENA 713|Rivastigmine bitartrate|ENA 713|Rivastigmine hydrogentartrate|Rivastigmine (tartrate)|(S)-3-(1-(Dimethylamino)ethyl)phenyl ethyl(methyl)carbamate (2R,3R)-2,3-dihydroxysuccinate|U

规格或纯度：≥98%

英文名称：Rivastigmine Tartrate

生化机理：Rivastigmine hydrogen tartrate is a parasympathomimetic or cholinergic agent. Rivastigmine hydrogen tartrate is also a dual ChEI (cholinesterase inhibitor); inhibiting BChE (butyrylcholinesterase) and AChE (acetylcholinesterase).Acetylcholinesterase and butyrylcholinesterase inhibitor. Reversibly forms covalent bonds with these enzymes. Parasympathomimetic or cholinergic agent. Active in vivo . Blood-brain barrier permeable.

应用：A parasympathomimetic or cholinergic agent.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。有毒，请参阅SDS以获取更多信息。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Rivastigmine Tartrate是一种胆碱酯酶抑制剂，IC50为5.5 μM，作为副交感神经或胆碱能剂，用于治疗轻度至中度阿尔茨海默病。A parasympathomimetic or cholinergic agent.Rivastigmine Tartrate is a cholinesterase inhibitor with IC50 of 5.5 μM, and used as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease.A parasympathomimetic or cholinergic agent.

IUPAC Name：(2R,3R)-2,3-dihydroxybutanedioic acid;[3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate

INCHI：InChI=1S/C14H22N2O2.C4H6O6/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4;5-1(3(7)8)2(6)4(9)10/h7-11H,6H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m01/s1

InChi Key：GWHQHAUAXRMMOT-MBANBULQSA-N

Canonical SMILES：CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C.C(C(C(=O)O)O)(C(=O)O)O

Isomeric SMILES：CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)C.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O

WGK Germany：3

RTECS：FA9550000

PubChem CID：6918078

溶解性：DMSO 42 mg/mL Water 80 mg/mL Ethanol 80 mg/mL

比旋光度：5° (C=5,MeOH)

熔点：126 °C

产品包装