产品名称

英文名称：Ginsenoside Rg3

同义词

20(S)-Ginsenoside Rg3 、 (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside、20 (S)-人参皂苷-Rg3 、 (3β,12β,20S)-12,20-二羟基达玛-24-烯-3-基2-O-β-D-吡喃葡萄糖基-β-D-吡喃葡萄糖苷 、 (3β, 12β）-12,20-二羟基 dmar-24-烯-3-基 2- O -β- D -吡喃葡萄糖基-β- D -吡喃葡萄糖苷

产品性质

CAS编号：14197-60-5

分子式：C42H72O13

分子量：785.01

PubChem编号：9918693

别名：20 (S)-人参皂苷-Rg3 | (3β,12β,20S)-12,20-二羟基达玛-24-烯-3-基2-O-β-D-吡喃葡萄糖基-β-D-吡喃葡萄糖苷 | (3β, 12β）-12,20-二羟基 dmar-24-烯-3-基 2- O -β- D -吡喃葡萄糖基-β- D -吡喃葡萄糖苷

英文别名：20(S)-Ginsenoside Rg3 | (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

规格或纯度：分析标准品,>98%

英文名称：Ginsenoside Rg3

生化机理：Ginsenoside Rg3 is a natural product isolated from ginseng. Similar to other ginsenosides, it has a cardioprotective effect. Ginsenoside Rg3 enhances cardiac, hERG (IKr), and KCNQ (Iks) channel currents through its interaction with the entrance of channel pores. It also inhibits palmitate induced insulinoma in MIN6N8 mice by regulating p44/42 MAPK activation β Apoptosis of cells. Ginsenoside Rg3 increases the level of transcription factor Nrf2 and induces mRNA levels of multidrug resistance associated proteins (Mrp) 1 and Mrp3. Rg3 regulates neuroinflammation by reducing the response of microglia to systemic LPS treatment. It activates AMPK in HepG2 cells, reduces lipid accumulation, and thus reduces the risk of cardiovascular disease caused by dyslipidemia.

储存温度：2-8°C储存,避光

运输条件：冰袋运输

IUPAC Name：(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

INCHI：InChI=1S/C42H72O13/c1-21(2)10-9-14-42(8,51)22-11-16-41(7)29(22)23(45)18-27-39(5)15-13-28(38(3,4)26(39)12-17-40(27,41)6)54-37-35(33(49)31(47)25(20-44)53-37)55-36-34(50)32(48)30(46)24(19-43)52-36/h10,22-37,43-51H,9,11-20H2,1-8H3/t22-,23+,24+,25+,26-,27+,28-,29-,30+,31+,32-,33-,34+,35+,36-,37-,39-,40+,41+,42-/m0/s1

InChi Key：RWXIFXNRCLMQCD-JBVRGBGGSA-N

Canonical SMILES：CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(C(O6)CO)O)O)O)C)C)O)C)O)C

Isomeric SMILES：CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)C)C)O)C)O)C

关联CAS：38243-03-7

PubChem CID：9918693

ChEBI：CHEBI67991

ChEMBL Ligand：CHEMBL398412

CAS Registry No.：14197-60-5

密度：1.3

敏感性：对湿度敏感，对光敏感，对热敏感

熔点：175-177oC

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowed

预防措施声明：P501,P264,P270,P330,P301+P317

产品包装