产品名称

英文名称：DL-Sulforaphane

同义词

sulforaphane、4478-93-7、DL-Sulforaphane、1-Isothiocyanato-4-(methylsulfinyl)butane、Sulforafan、D,L-Sulforaphane、1-Isothiocyanato-4-(methylsulfinyl)-butane、1-isothiocyanato-4-methylsulfinylbutane、Butane, 1-isothiocyanato-4-(methylsulfinyl)-、(+/-)-sulforaphane、莱菔硫烷、1-异硫氰酸基-4-(甲亚磺酰基)-丁烷、莱菔硫烷

产品性质

CAS编号：4478-93-7

分子式：C6H11NOS2

分子量：177.29

MDL号：MFCD00198068

PubChem编号：5350

别名：莱菔硫烷|1-异硫氰酸基-4-(甲亚磺酰基)-丁烷|莱菔硫烷

英文别名：sulforaphane|4478-93-7|DL-Sulforaphane|1-Isothiocyanato-4-(methylsulfinyl)butane|Sulforafan|D,L-Sulforaphane|1-Isothiocyanato-4-(methylsulfinyl)-butane|1-isothiocyanato-4-methylsulfinylbutane|Butane, 1-isothiocyanato-4-(methylsulfinyl)-|(+/-)-sulforaphane

规格或纯度：95%

英文名称：DL-Sulforaphane

生化机理：具有抗癌特性的II相解毒酶的选择性诱导物。在十字花科蔬菜（包括西兰花）中发现的有机硫化合物。 萝卜硫素是一种在十字花科蔬菜中发现的抗癌、抗微生物和抗糖尿病化合物。它可诱导产生解毒酶，例如可引起异生素转化的醌还原酶和谷胱甘肽S-转移酶。萝卜硫素还可增加肿瘤抑制蛋白的转录并抑制组蛋白脱乙酰酶的活性。它通过抑制LPS介导的iNOS、COX-2、IL-1β 和TNF-α的表达来调节炎症反应。

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：产品介绍Sulforaphane 是一种天然存在的异硫氰酸盐，存在于十字花科蔬菜如西兰花、卷心菜、羽衣甘蓝。它是 Nrf2 的诱导物。Sulforaphane 也是 histone deacetylase (HDAC) 和 NF-κB 的抑制剂。Sulforaphane 可增加 heme oxygenase-1 (HO-1)，并降低 reactive oxygen species (ROS) 的水平。Sulforaphane 诱导细胞周期停滞和凋亡。用途用DL-萝卜硫素处理LNCaP前列腺癌细胞以研究其对雄激素受体的作用。用DL-萝卜硫素处理大鼠对研究其对马拉硫磷毒性的影响。Product IntroductionSulforaphane is a naturally occurring isothiocyanate found in cruciferous vegetables such as broccoli, cabbage, kale.It is an inducer of Nrf2.Sulforaphane is also an inhibitor of histone deacetylase (HDAC) and NF - κ B.Sulforaphane increases heme oxygenase-1 (HO-1) and decreases the levels of reactive oxygen species (ROS).Sulforaphane induces cell cycle arrest and apoptosis.ApplicationLNCaP prostate cancer cells were treated with DL sulforaphane to investigate its effect on androgen receptor.Treatment of rats with DL sulforaphane was used to study its effect on malathion toxicity.

IUPAC Name：1-isothiocyanato-4-methylsulfinylbutane

INCHI：InChI=1S/C6H11NOS2/c1-10(8)5-3-2-4-7-6-9/h2-5H2,1H3

InChi Key：SUVMJBTUFCVSAD-UHFFFAOYSA-N

Canonical SMILES：CS(=O)CCCCN=C=S

Isomeric SMILES：CS(=O)CCCCN=C=S

WGK Germany：3

PubChem CID：5350

ChEBI：CHEBI47807

CAS Registry No.：4478-93-7

Wikipedia：Sulforaphane

溶解性：Soluble in Chloroform, Dichloromethane, Diethyl Ether, methanol and DMSO, Soluble in Chloroform, Dichloromethane, Diethyl Ether, methanol and DMSO

密度：1.17

敏感性：对湿度、光线敏感

个人防护装备：Eyeshields,Gloves,half-mask respirator (EU),half-mask respirator (US),multi-purpose combination respirator cartridge (US)

产品包装