产品名称

英文名称：Aliskiren

同义词

Aliskiren、173334-57-1、Rasilez、SPP100、SPP 100、Aliskiren(CGP 60536)、UNII-502FWN4Q32、CGP60536B、HSDB 7843、SPP-100、Aliskiren fumarate、CHEBI601027、502FWN4Q32、CGP-060536B、CHEMBL1639、(2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethylethyl)-4-hydroxy-7-{[4-methoxy

产品性质

CAS编号：173334-57-1

分子式：C30H53N3O6

分子量：551.77

PubChem编号：5493444

英文别名：Aliskiren|173334-57-1|Rasilez|SPP100|SPP 100|Aliskiren(CGP 60536)|UNII-502FWN4Q32|CGP60536B|HSDB 7843|SPP-100|Aliskiren fumarate|CHEBI601027|502FWN4Q32|CGP-060536B|CHEMBL1639|(2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethylethyl)-4-hydroxy-7-{[4-methoxy

规格或纯度：≥98%

英文名称：Aliskiren

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：Aliskiren(CGP 60536)是肾素抑制剂，IC50为1.5 nM。Aliskiren(CGP 60536) is a direct renin inhibitor with IC50 of 1.5 nM.

IUPAC Name：(2S,4S,5S,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-propan-2-ylnonanamide

INCHI：InChI=1S/C30H53N3O6/c1-19(2)22(14-21-10-11-26(38-8)27(15-21)39-13-9-12-37-7)16-24(31)25(34)17-23(20(3)4)28(35)33-18-30(5,6)29(32)36/h10-11,15,19-20,22-25,34H,9,12-14,16-18,31H2,1-8H3,(H2,32,36)(H,33,35)/t22-,23-,24-,25-/m0/s1

InChi Key：UXOWGYHJODZGMF-QORCZRPOSA-N

Canonical SMILES：CC(C)C(CC1=CC(=C(C=C1)OC)OCCCOC)CC(C(CC(C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N

Isomeric SMILES：CC(C)[C@@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[C@@H]([C@H](C[C@@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N

PubChem CID：5493444

DrugBank Ligand：DB01258

CAS Registry No.：173334-57-1

Wikipedia：Aliskiren

ChEBI：CHEBI601027

ChEMBL Ligand：CHEMBL1639

RCSB PDB Ligand：C41

PEP：aliskiren

DrugCentral Ligand：119

溶解性：DMSO

象形图：

信号词：Warning

危险声明：H412 Harmful to aquatic life with long lasting effectsH317 May cause an allergic skin reactionH400 Very toxic to aquatic lifeH410 Very toxic to aquatic life with long lasting effects

预防措施声明：P261,P273,P280,P302+P352,P321,P501,P272,P333+P313,P362+P364,P391

产品包装