产品名称

英文名称：sitagliptin

同义词

MK-0431、(3R)-3-amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one、1,2,4-TRIAZOLO(4,3-A)PYRAZINE-7(8H)-PROPANAMINE, 5,6-DIHYDRO-gamma-OXO-3-(TRIFLUOROMETHYL)-alpha-((2,4,5-TRIFLUOROPHENYL)ME、西他列汀

产品性质

CAS编号：486460-32-6

分子式：C16H15F6N5O

分子量：407.3136

PubChem编号：4369359

别名：西他列汀

英文别名：MK-0431|(3R)-3-amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one|1,2,4-TRIAZOLO(4,3-A)PYRAZINE-7(8H)-PROPANAMINE, 5,6-DIHYDRO-gamma-OXO-3-(TRIFLUOROMETHYL)-alpha-((2,4,5-TRIFLUOROPHENYL)ME

规格或纯度：97%

英文名称：sitagliptin

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：Sitagliptin 是一种有效的 DPP4 抑制剂，在 Caco-2 细胞中，IC50 值为 19 nM。

IUPAC Name：(3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one

INCHI：InChI=1S/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1

InChi Key：MFFMDFFZMYYVKS-SECBINFHSA-N

Canonical SMILES：C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)CC(CC3=CC(=C(C=C3F)F)F)N

Isomeric SMILES：C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N

PubChem CID：4369359

DrugBank Ligand：DB07214

ChEMBL Ligand：CHEMBL1422

Wikipedia：Sitagliptin

CAS Registry No.：486460-32-6

ChEBI：CHEBI40237

RCSB PDB Ligand：715

PEP：sitagliptin

DrugCentral Ligand：2448

象形图：

信号词：Danger

危险声明：H319 Causes serious eye irritationH373 Causes damage to organs through prolonged or repeated exposure

预防措施声明：P305+P351+P338,P280,P501

产品包装