产品名称

英文名称：calcitriol

同义词

calcitriol、Rocaltrol、Calcijex、32222-06-3、Topitriol、1alpha,25-Dihydroxyvitamin D3、Silkis、1alpha,25-Dihydroxycholecalciferol、Soltriol、Vectical、1,25-DHCC、Calcitriolum、1,25-DIHYDROXYCHOLECALCIFEROL、1,25-Dihydroxyvitamin D3、1,25-Dihydroxyvitamin D、1alpha,25(OH、骨化三醇、1α,25-二羟基维他命D3、1,25-二羟基胆钙化醇

产品性质

CAS编号：32222-06-3

分子式：C27H44O3

分子量：416.64

Beilstein号：7559394

EC号：250-963-8

MDL号：MFCD00867079

PubChem编号：5280453

别名：骨化三醇|1α,25-二羟基维他命D3|1,25-二羟基胆钙化醇

英文别名：calcitriol|Rocaltrol|Calcijex|32222-06-3|Topitriol|1alpha,25-Dihydroxyvitamin D3|Silkis|1alpha,25-Dihydroxycholecalciferol|Soltriol|Vectical|1,25-DHCC|Calcitriolum|1,25-DIHYDROXYCHOLECALCIFEROL|1,25-Dihydroxyvitamin D3|1,25-Dihydroxyvitamin D|1alpha,25(OH

规格或纯度：97%

英文名称：calcitriol

生化机理：Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D.Active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) displays calcemic actions. Calcitriol stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. Calcitriol (1,25-Dihydroxyvitamin D3; Rocaltrol )exhibits antitumor activity; Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells.

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

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ALogP：5.1

PubChem SID：488195207

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488195207

IUPAC Name：(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

INCHI：InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1

InChi Key：GMRQFYUYWCNGIN-NKMMMXOESA-N

Canonical SMILES：CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C

Isomeric SMILES：C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](C[C@@H](C3=C)O)O)C

WGK Germany：3

RTECS：FZ4645000

PubChem CID：5280453

Reaxy-Rn：2227647

DrugBank Ligand：DB00136

CAS Registry No.：32222-06-3

Wikipedia：Calcitriol

ChEBI：CHEBI17823

ChEMBL Ligand：CHEMBL846

NURSA Ligand：10.1621/DBD1JWZA3G

RCSB PDB Ligand：VDX

PEP：calcitrol

DrugCentral Ligand：466

敏感性：对空气敏感，对热敏感

熔点：119°C(lit.)

象形图：

信号词：Danger

危险声明：H300 Fatal if swallowedH310 Fatal in contact with skinH330 Fatal if inhaledH361 Suspected of damaging fertility or the unborn child

预防措施声明：P280,P302+P352,P321,P405,P501,P264,P260,P284,P271,P270,P304+P340,P403+P233,P330,P262,P320,P361+P364,P203,P301+P316,P318,P316

Merck Index：1644

个人防护装备：Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

产品包装