产品名称

英文名称：1,2-Dioctanoyl-sn-glycerol

同义词

1,2-dioctanoyl-sn-glycerol、60514-48-9、sn-1,2-Dioctanoylglycerol、Dicaprylglyceride、(S)-3-Hydroxypropane-1,2-diyl dioctanoate、1,2-Dicapryloyl-sn-glycerol、D-alpha,beta-Dicaprylin、[(2S)-3-hydroxy-2-octanoyloxypropyl] octanoate、CHEMBL55267、CHEBI76979、Octanoic、(S)-甘油 1,2-二辛酸酯

产品性质

CAS编号：60514-48-9

分子式：C19H36O5

分子量：344.49

Beilstein号：1714754

MDL号：MFCD00036835

PubChem编号：148879

别名：(S)-甘油 1,2-二辛酸酯

英文别名：1,2-dioctanoyl-sn-glycerol|60514-48-9|sn-1,2-Dioctanoylglycerol|Dicaprylglyceride|(S)-3-Hydroxypropane-1,2-diyl dioctanoate|1,2-Dicapryloyl-sn-glycerol|D-alpha,beta-Dicaprylin|[(2S)-3-hydroxy-2-octanoyloxypropyl] octanoate|CHEMBL55267|CHEBI76979|Octanoic

规格或纯度：≥96%

英文名称：1,2-Dioctanoyl-sn-glycerol

生化机理：Cell-permeable, diacylglycerol (DAG) analog, and activator of protein kinase C (PKC). Shown to possess a lower affinity for the α isoform of PKC than for the other isoforms. Mimics the action of tumor-promoting phorbol esters, such as phorbol 12-myristate 13-acetate (PMA). Inhibits slow (L-type) Ca2+ current in rat heart cells independently of PKC activation and also inhibits the cGMP-gated channel in rod outer segments by a phosphorylation-independent mechanism.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货；如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：1,2-Dioctanoyl-sn-glycerol is a cell-permeable activator of PKC (protein kinase C). Exhibits lower affinity for PKCa than for other isozymes. Shown to mimic the effects of tumor-promoting phorbol diesters on mitogenesis and epidermal growth factor binding and action in intact cells.To study its stimulatory effect on protein kinase C (PKC) in human cell linesAs a lipid cofactor in PKC activity assayIn vesicular-fusion protein Sec-18 binding studies

IUPAC Name：[(2S)-3-hydroxy-2-octanoyloxypropyl] octanoate

INCHI：InChI=1S/C19H36O5/c1-3-5-7-9-11-13-18(21)23-16-17(15-20)24-19(22)14-12-10-8-6-4-2/h17,20H,3-16H2,1-2H3/t17-/m0/s1

InChi Key：ZQBULZYTDGUSSK-KRWDZBQOSA-N

Canonical SMILES：CCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCC

Isomeric SMILES：CCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCC

PubChem CID：148879

溶解性：Soluble in DMSO (7 mg/ml), chloroform, 100% ethanol, dichloromethane, ether, ethyl acetate, methanol, most organic solvents, DMF (7 mg/ml), PBS (pH 7.2) (250 ug/ml), water (>250 ug/ml) at 25 °C, and cyclohexane.

沸点：81-82° C

产品包装