产品名称

英文名称：2-Deoxy-D-glucose

同义词

5CFA0332-FB70-485D-A064-6C4C39E7CBA1、2 Deoxy D glucose、2-DEOXY-D-GLUCOSE [HSDB]、EINECS 205-823-0、2-Deoxy-D-mannose、2-Deoxy-D-arabino-hexose;D-Arabino-2-deoxyhexose、3,3-bis(4-hydroxy-2-methyl-5-propan-2-ylphenyl)-2-benzouran-1-one、D-2-Deoxyglucose、2-Desoxy、2-去氧-D-葡萄糖

产品性质

CAS编号：154-17-6

分子式：C6H12O5

分子量：164.16

Beilstein号：1723331

EC号：205-823-0

MDL号：MFCD00151328

PubChem编号：108223

别名：2-去氧-D-葡萄糖

英文别名：5CFA0332-FB70-485D-A064-6C4C39E7CBA1|2 Deoxy D glucose|2-DEOXY-D-GLUCOSE [HSDB]|EINECS 205-823-0|2-Deoxy-D-mannose|2-Deoxy-D-arabino-hexose;D-Arabino-2-deoxyhexose|3,3-bis(4-hydroxy-2-methyl-5-propan-2-ylphenyl)-2-benzouran-1-one|D-2-Deoxyglucose|2-Desoxy

规格或纯度：98%

英文名称：2-Deoxy-D-glucose

生化机理：2-Deoxy-D-Glucose (2-Deoxyglucose) is a glucose analog that inhibits glycolysis via its actions on hexokinase, the rate limiting step of glycolysis. It is phosphorylated by hexokinase to 2-DG-P which can not be further metabolized by phosphoglucose isomerase. This leads to the accumulation of 2-DG-P in the cell and the depletion in cellular ATP. In vitro, 2-Deoxyglucose has been shown to induce autophagy, increase ROS production, and activate AMPK.Non-metabolizable glucose analog and glycolytic inhibitor. Competitive phosphoglucose isomerase inhibitor. Induces ROS-dependent autophagy (EC 50 = 100 μM) and depletes cellular ATP. Antitumor and antiproliferative activity in vivo and in vitro. Orally ac

应用：2-脱氧-D-葡萄糖（2-Deoxy-D-Glucose，2-DG）为天然抗代谢物类抗生素，具有能够抑制病毒感染、酵母发酵、致病菌及肿瘤细胞生长等。

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：溶于水和乙醇。2-脱氧-D-葡萄糖（2-Deoxy-D-Glucose，2-DG）为天然抗代谢物类抗生素，具有能够抑制病毒感染、酵母发酵、致病菌及肿瘤细胞生长等。2-Deoxy-D-glucose is used in the development of anti-cancer strategies that involve radio- and chemosensitization and oxidative stress.

PubChem SID：488187422

IUPAC Name：(3R,4S,5R)-3,4,5,6-tetrahydroxyhexanal

INCHI：InChI=1S/C6H12O5/c7-2-1-4(9)6(11)5(10)3-8/h2,4-6,8-11H,1,3H2/t4-,5-,6+/m1/s1

InChi Key：VRYALKFFQXWPIH-PBXRRBTRSA-N

Canonical SMILES：C(C=O)C(C(C(CO)O)O)O

Isomeric SMILES：C(C=O)[C@H]([C@@H]([C@@H](CO)O)O)O

WGK Germany：3

RTECS：MQ3325000

PubChem CID：108223

Reaxy-Rn：1723331

溶解性：Soluble in water.

密度：1.533

比旋光度：46.5 ° (C=1, H2O)

熔点：146-147°C

Merck Index：2904

个人防护装备：Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

产品包装