产品名称

英文名称：L-Dihydroorotic acid

同义词

L-Dihydroorotic acid、5988-19-2、(S)-2,6-Dioxohexahydropyrimidine-4-carboxylic acid、L-dihydroorotate、Hydroorotic acid, L-、L-Hydroorotic acid、(S)-dihydroorotic acid、(S)-dihydroorotate、(4S)-2,6-dioxo-1,3-diazinane-4-carboxylic acid、L-5,6-dihydroorotic acid、Di、L-二氢乳清酸、2,6-二氧六氢-4-嘧啶羧酸、L-氢乳清酸、二氢-L-乳清酸

产品性质

CAS编号：5988-19-2

分子式：C5H6N2O4

分子量：158.11

MDL号：MFCD00085339

PubChem编号：439216

别名：L-二氢乳清酸|2,6-二氧六氢-4-嘧啶羧酸|L-氢乳清酸|二氢-L-乳清酸

英文别名：L-Dihydroorotic acid|5988-19-2|(S)-2,6-Dioxohexahydropyrimidine-4-carboxylic acid|L-dihydroorotate|Hydroorotic acid, L-|L-Hydroorotic acid|(S)-dihydroorotic acid|(S)-dihydroorotate|(4S)-2,6-dioxo-1,3-diazinane-4-carboxylic acid|L-5,6-dihydroorotic acid|Di

规格或纯度：≥98%

英文名称：L-Dihydroorotic acid

生化机理：L-二氢乳清酸(DHO)是二氢乳清酸脱氢酶(DHODH)的底物，而DHODH是一种从头合成嘧啶的酶。抑制剂对DHOH的抑制作用会导致上游代谢物DHO大量积累和尿苷水平下降。因此，DHO和尿苷可作为嘧啶合成的生物标志物，用于临床开发DHOH抑制剂。

储存温度：2-8°C储存

运输条件：冰袋运输

产品介绍：应用L-二氢乳清酸(DHO)用作二氢乳清酸脱氢酶(DHODH)检测的底物。ApplicationL-Dihydroorotic acid has been used as a substrate in dihydroorotate dehydrogenase (DHODH) assay.

PubChem SID：488189736

IUPAC Name：(4S)-2,6-dioxo-1,3-diazinane-4-carboxylic acid

INCHI：InChI=1S/C5H6N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h2H,1H2,(H,9,10)(H2,6,7,8,11)/t2-/m0/s1

InChi Key：UFIVEPVSAGBUSI-REOHCLBHSA-N

Canonical SMILES：C1C(NC(=O)NC1=O)C(=O)O

Isomeric SMILES：C1[C@H](NC(=O)NC1=O)C(=O)O

WGK Germany：3

PubChem CID：439216

溶解性：Soluble in water (partly), and dimethyl formamide.

熔点：254-255°C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

产品包装