产品名称

英文名称：Clopamide

同义词

clopamide、636-54-4、Clopamidum、Brinaldix、Adurix、Aquex、Chlosudimeprimyl、Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,6-dimethyl-1-piperidinyl)-, cis-、MLS000028574、17S83WON0I、4-Chloro-N-(2,6-dimethylpiperidino)-3-sulfamoylbenzamide、4-Chloro-N-(cis-2,6-dimethyl、氯哌酰胺、克罗帕米

产品性质

CAS编号：636-54-4

分子式：C14H20ClN3O3S

分子量：345.84

EC号：211-261-7

MDL号：MFCD00941495

PubChem编号：12492

别名：氯哌酰胺|克罗帕米

英文别名：clopamide|636-54-4|Clopamidum|Brinaldix|Adurix|Aquex|Chlosudimeprimyl|Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,6-dimethyl-1-piperidinyl)-, cis-|MLS000028574|17S83WON0I|4-Chloro-N-(2,6-dimethylpiperidino)-3-sulfamoylbenzamide|4-Chloro-N-(cis-2,6-dimethyl

规格或纯度：98%

英文名称：Clopamide

生化机理：选择性Na + / 2Cl-共转运蛋白抑制剂。体内利尿活性。口服具有活性

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Clopamide is shown to selectively inhibit the NCCT (sodium chloride cotransporter). After Hypokalemia was more marked with chronic administration to hypertension patients. Reported to considerably elevate the mean blood glucosein diabetic patients not receiving insulin. Also reported to lower body weight and blood pressure, and raise blood urea in diabetic patients.A compound that selectively inhibit the sodium chloride cotransporter.Clopamide is shown to selectively inhibit the NCCT (sodium chloride cotransporter). After Hypokalemia was more marked with chronic administration to hypertension patients. Reported to considerably elevate the mean blood glucosein diabetic patients not receiving insulin. Also reported to lower body weight and blood pressure, and raise blood urea in diabetic patients.A compound that selectively inhibit the sodium chloride cotransporter.

IUPAC Name：4-chloro-N-[(2R,6S)-2,6-dimethylpiperidin-1-yl]-3-sulfamoylbenzamide

INCHI：InChI=1S/C14H20ClN3O3S/c1-9-4-3-5-10(2)18(9)17-14(19)11-6-7-12(15)13(8-11)22(16,20)21/h6-10H,3-5H2,1-2H3,(H,17,19)(H2,16,20,21)/t9-,10+

InChi Key：LBXHRAWDUMTPSE-AOOOYVTPSA-N

Canonical SMILES：CC1CCCC(N1NC(=O)C2=CC(=C(C=C2)Cl)S(=O)(=O)N)C

Isomeric SMILES：C[C@@H]1CCC[C@@H](N1NC(=O)C2=CC(=C(C=C2)Cl)S(=O)(=O)N)C

WGK Germany：3

PubChem CID：12492

溶解性：Soluble in DMSO (20 mg/mL), ethanol (5 mg/mL warm), and water (partly miscible).

熔点：248-249℃

象形图：

信号词：Danger

危险声明：H317 May cause an allergic skin reactionH334 May cause allergy or asthma symptoms or breathing difficulties if inhaled

预防措施声明：P261,P280,P302+P352,P321,P501,P284,P304+P340,P272,P333+P313,P362+P364,P342+P316

个人防护装备：dust mask type N95 (US), Eyeshields, Faceshields, Gloves

产品包装