产品名称

英文名称：Ribavirin

同义词

ribavirin、36791-04-5、Tribavirin、Rebetol、Virazole、Copegus、Vilona、Ribamidil、Ribasphere、Ribavirine、Viramid、Ribamidyl、RTCA、Varazid、Ribavirina、Ribavirinum、Cotronak、Ribamide、Virazid、1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide、Ribavirin Mylan、Ribavirine、三氮唑核苷、1-β-D-呋喃核糖-1,2,4-三氮唑-3-羟酰胺、病毒唑、利巴韦林、1-β-D-呋喃核糖基-1,2,4-三唑-3-甲酰胺

产品性质

CAS编号：36791-04-5

分子式：C8H12N4O5

分子量：244.2

MDL号：MFCD00058564

PubChem编号：37542

别名：三氮唑核苷|1-β-D-呋喃核糖-1,2,4-三氮唑-3-羟酰胺|病毒唑|利巴韦林|1-β-D-呋喃核糖基-1,2,4-三唑-3-甲酰胺

英文别名：ribavirin|36791-04-5|Tribavirin|Rebetol|Virazole|Copegus|Vilona|Ribamidil|Ribasphere|Ribavirine|Viramid|Ribamidyl|RTCA|Varazid|Ribavirina|Ribavirinum|Cotronak|Ribamide|Virazid|1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide|Ribavirin Mylan|Ribavirine

规格或纯度：98%

英文名称：Ribavirin

生化机理：一种无干扰素的广谱抗病毒核苷。活性代谢物干扰病毒复制。对多种病毒显示抗病毒活性，包括丙型肝炎，流感和小儿麻痹症。

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Ribavirin is a non-interferon-inducing, broad spectrum antiviral nucleoside. Ribavirin is reported to be active against RSV, HIV, HCV, and other infectious agents. The compound’s metabolite, ribavirin-5′-phosphate, inhibits inosine monophosphate (IMP) dehydrogenase.A broad spectrum antiviral nucleoside and inhibitor of inosine monophosphate dehydrogenase.Ribavirin is a non-interferon-inducing, broad spectrum antiviral nucleoside. Ribavirin is reported to be active against RSV, HIV, HCV, and other infectious agents. The compound’s metabolite, ribavirin-5′-phosphate, inhibits inosine monophosphate (IMP) dehydrogenase.A broad spectrum antiviral nucleoside and inhibitor of inosine monophosphate dehydrogenase.

ALogP：-1.8

IUPAC Name：1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide

INCHI：InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1

InChi Key：IWUCXVSUMQZMFG-AFCXAGJDSA-N

Canonical SMILES：C1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N

Isomeric SMILES：C1=NC(=NN1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)C(=O)N

WGK Germany：3

RTECS：XZ4250000

PubChem CID：37542

Reaxy-Rn：892462

DrugBank Ligand：DB00811

CAS Registry No.：36791-04-5

ChEMBL Ligand：CHEMBL1643

Wikipedia：Ribavirin

ChEBI：CHEBI63580

RCSB PDB Ligand：RBV

Reactome Reaction：R-HSA-9678749, R-HSA-9680836

Reactome Drug：R-ALL-9680963

DrugCentral Ligand：2373

溶解性：Soluble in water (20 mg/ml), DMSO (49 mg/ml at 25 °C), ethanol (<1 mg/ml at 25 °C), and alcohol (slightly).

密度：2.08

比旋光度：-36 ° (C=1, H2O)

熔点：176°C

象形图：

信号词：Danger

危险声明：H319 Causes serious eye irritationH335 May cause respiratory irritationH341 Suspected of causing genetic defectsH373 Causes damage to organs through prolonged or repeated exposureH412 Harmful to aquatic life with long lasting effectsH317 May cause an allergic skin reactionH360 May damage fertility or the unborn childH361 Suspected of damaging fertility or the unborn child

预防措施声明：P261,P305+P351+P338,P273,P280,P302+P352,P321,P405,P501,P260,P281,P271,P304+P340,P403+P233,P272,P333+P313,P362+P364,P203,P264+P265,P318,P337+P317,P319

Merck Index：8198

个人防护装备：Eyeshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges

产品包装