产品名称

英文名称：Mupirocin

同义词

Mupirocin、12650-69-0、Pseudomonic acid、Bactroban、Mupirocine、Centany、Pseudomonic acid A、Bactoderm、Mupirocina、Mupirocinum、Turixin、BRL 4910A、BRL-4910A、trans-Pseudomonic acid、9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxir、莫匹罗星、假单胞菌酸

产品性质

CAS编号：12650-69-0

分子式：C26H44O9

分子量：500.62

EC号：231-791-2

MDL号：MFCD01711620

PubChem编号：446596

别名：莫匹罗星|假单胞菌酸

英文别名：Mupirocin|12650-69-0|Pseudomonic acid|Bactroban|Mupirocine|Centany|Pseudomonic acid A|Bactoderm|Mupirocina|Mupirocinum|Turixin|BRL 4910A|BRL-4910A|trans-Pseudomonic acid|9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxir

规格或纯度：95%

英文名称：Mupirocin

生化机理：窄谱抗生素剂。与异亮氨酰t-RNA合成酶结合并抑制蛋白质合成。在体内显示出对革兰氏阳性细菌的剂量依赖性抑菌和杀菌作用。

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

备注：25mg/100mg卖完停产，不再备货 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Pseudomonic Acid, also known as mupirocin, is an antibiotic isolated from Pseudomonas fluorescens which strongly inhibits protein and RNA synthesis. Inhibition of protein synthesis was reversed by isoleucine and Pseudomonic Acid was shown to inhibit IleRS (isoleucyl-tRNA synthetase) in vitro. Pseudomonic Acid also demonstrates weak inhibitory action on FARSL (phenylalanyl-tRNA synthetase). Efficacy against staphylococci and streptococci including multiply resistant Staphylcoccus aureus and Staphylococcus epidermidis is reported with Pseudomonic Acid.An antibiotic inhibitor of isoleucyl-tRNA synthetaseProduct DescribtionPseudomonic Acid, also known as mupirocin, is an antibiotic isolated from Pseudomonas fluorescens which strongly inhibits protein and RNA synthesis. Inhibition of protein synthesis was reversed by isoleucine and Pseudomonic Acid was shown to inhibit IleRS (isoleucyl-tRNA synthetase) in vitro. Pseudomonic Acid also demonstrates weak inhibitory action on FARSL (phenylalanyl-tRNA synthetase). Efficacy against staphylococci and streptococci including multiply resistant Staphylcoccus aureus and Staphylococcus epidermidis is reported with Pseudomonic Acid.An antibiotic inhibitor of isoleucyl-tRNA synthetaseProduct ApplicationMupirocin is involved in inhibition of protein synthesis was reversed by isoleucine and Pseudomonic Acid was shown to inhibit IleRS (isoleucyl-tRNA synthetase) in vitro. It also demonstrates weak inhibitory action on FARSL (phenylalanyl-tRNA synthetase). Efficacy against staphylococci and streptococci including multiply resistant Staphylcoccus aureus and Staphylococcus epidermidis is reported with Pseudomonic Acid.

ALogP：3

IUPAC Name：9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl]oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid

INCHI：InChI=1S/C26H44O9/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29)/b16-13+/t17-,18-,19-,20-,21-,24+,25-,26-/m0/s1

InChi Key：MINDHVHHQZYEEK-HBBNESRFSA-N

Canonical SMILES：CC(C1C(O1)CC2COC(C(C2O)O)CC(=CC(=O)OCCCCCCCCC(=O)O)C)C(C)O

Isomeric SMILES：C[C@H]([C@H]1[C@@H](O1)C[C@H]2CO[C@H]([C@@H]([C@@H]2O)O)C/C(=C/C(=O)OCCCCCCCCC(=O)O)/C)[C@H](C)O

WGK Germany：2

RTECS：RA6907000

PubChem CID：446596

CAS Registry No.：12650-69-0

ChEMBL Ligand：CHEMBL719

BindingDB Ligand：50290686

DrugBank Ligand：DB00410

DrugCentral Ligand：1857

溶解性：Soluble in ethanol, methanol, DMF, DMSO (≥ 10 mg/ml), and water (limited).

密度：1.183

敏感性：对空气敏感，吸湿

比旋光度：-19° (C=1,MeOH)

沸点：672℃

熔点：78 °C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH302 Harmful if swallowedH317 May cause an allergic skin reaction

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P501,P264,P270,P272,P333+P313,P362+P364,P330,P264+P265,P301+P317,P337+P317,P332+P317

Merck Index：6302

个人防护装备：Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

产品包装