产品名称

英文名称：Bromobimane

同义词

Monobromobimane、Bromobimane、71418-44-5、MBBR、Thiolyte MB、Bimane monobromide、CHEBI62825、V23UK0CYXL、7-(bromomethyl)-1,2,6-trimethylpyrazolo[1,2-a]pyrazole-3,5-dione、3-(Bromomethyl)-2,5,6-trimethylpyrazolo[1,2-a]pyrazole-1,7-dione、NSC-608544、1H,7H-Pyrazolo(1、单溴代双满、单溴代二苯甲烷、3-(溴甲基)-2,5,6-三甲基吡唑并[1,2-a]吡唑-1,7-二酮

产品性质

CAS编号：71418-44-5

分子式：C10H11BrN2O2

分子量：271.11

Beilstein号：4430959

MDL号：MFCD00036951

PubChem编号：114810

别名：单溴代双满|单溴代二苯甲烷|3-(溴甲基)-2,5,6-三甲基吡唑并[1,2-a]吡唑-1,7-二酮

英文别名：Monobromobimane|Bromobimane|71418-44-5|MBBR|Thiolyte MB|Bimane monobromide|CHEBI62825|V23UK0CYXL|7-(bromomethyl)-1,2,6-trimethylpyrazolo[1,2-a]pyrazole-3,5-dione|3-(Bromomethyl)-2,5,6-trimethylpyrazolo[1,2-a]pyrazole-1,7-dione|NSC-608544|1H,7H-Pyrazolo(1

规格或纯度：≥95.0%

英文名称：Bromobimane

生化机理：溶液形式的溴代双满可与小分子硫醇基（如 GSH）和反应性蛋白硫醇基（如血红蛋白）反应。溴代双满与硫醇的反应为二级pH依赖性反应，且在与硫醇盐反应后，可活化水溶性荧光产物以便检测

应用：溴乙烷在体内和体外已用于定量测定游离硫化氢 。已用于标记含巯基的蛋白质。

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：溴代双满又称单溴联苯胺。它还是一种已知的硫醇探针，是一种在光解反应后活化的荧光试剂应用溴代双满用于高效液相色谱法硫醇测定,适于荧光测定2，3-二巯基丙烷-1-磺酸和其他二硫醇。溴代双满已用作研究牛心线粒体寡霉素敏感性 ATP 酶的荧光标记Bromobimane is a fluorescent probe that readily reacts with low molecular weight and protein thiols. It is almost non-fluorescent until it is conjugated to thiol. The reagent is particularly useful for quantifying glutathione.Thiol-reactive fluorescent probeApplicationBromodimethamine is used for the determination of mercaptan by high performance liquid chromatography and is suitable for the fluorescence determination of 2, 3-dimercaptopropane-1-sulfonic acid and other dimercaptan. Bromodimethamine has been used as a fluorescent label for the study of oligomycin sensitive ATPase in bovine heart mitochondria

PubChem SID：488187516

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488187516

IUPAC Name：7-(bromomethyl)-1,2,6-trimethylpyrazolo[1,2-a]pyrazole-3,5-dione

INCHI：InChI=1S/C10H11BrN2O2/c1-5-7(3)12-8(4-11)6(2)10(15)13(12)9(5)14/h4H2,1-3H3

InChi Key：AHEWZZJEDQVLOP-UHFFFAOYSA-N

Canonical SMILES：CC1=C(N2C(=C(C(=O)N2C1=O)C)CBr)C

Isomeric SMILES：CC1=C(N2C(=C(C(=O)N2C1=O)C)CBr)C

PubChem CID：114810

溶解性：Soluble in water (partly), DMSO, DMF, methanol (25 mg/ml), and chloroform.

密度：1.7

敏感性：对光敏感;对热敏感

折光率：1.64

沸点：327.8° C

熔点：161°C

产品包装