产品名称

英文名称：(-)-Epicatechin gallate

同义词

(-)-Epicatechin gallate、1257-08-5、Epicatechin gallate、(-)-Epicatechin-3-O-gallate、(-)-epicatechingallate、L-Epicatechin gallate、epicatechin monogallate、(-)-Epicatechin-3-gallate、Teatannin、(-)-Epicatechin 3-O-gallate、Epicatechol, gallate、ECG、3-O-Galloylepic

产品性质

CAS编号：1257-08-5

分子式：C22H18O10

分子量：442.37

EC号：603-088-4

MDL号：MFCD00075936

PubChem编号：107905

英文别名：(-)-Epicatechin gallate|1257-08-5|Epicatechin gallate|(-)-Epicatechin-3-O-gallate|(-)-epicatechingallate|L-Epicatechin gallate|epicatechin monogallate|(-)-Epicatechin-3-gallate|Teatannin|(-)-Epicatechin 3-O-gallate|Epicatechol, gallate|ECG|3-O-Galloylepic

规格或纯度：98%

英文名称：(-)-Epicatechin gallate

生化机理：(-)Epicatechin gallate is a polyphenol apoptosis inducer in tumor cells commonly found in green tea. Studies sμggest that (-)Epicatechin gallate causes anti-proliferative and anti-inflammatory effects on pancreatic ductal adenocarcinoma cells. Alternate studies show that (-)Epicatechin gallate can suppress H2O2-induced genotoxicity in vitro in C6 astroglial cells. In contrast at high concentrations polyphenols are shown to reverse the genoprotective effects that they produce at low concentrations. Furthermore, (-)Epicatechin gallate can inhibit the development of mouse blastocysts via apoptosis. Studies indicate that (-)Epicatechin gallate binds to the cell membrane in methicillin-resistant Staphylococcus aureus which decreases the fluidity of the bilayer and induces changes in gene expression.

应用：An antioxidant investigated as an adjunct treatment of some methyicillin resistant bacteria.

储存温度：2-8°C储存

运输条件：冰袋运输

产品介绍：An antioxidant investigated as an adjunct treatment of some methyicillin resistant bacteria.An antioxidant investigated as an adjunct treatment of some methyicillin resistant bacteria.

IUPAC Name：[(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate

INCHI：InChI=1S/C22H18O10/c23-11-6-14(25)12-8-19(32-22(30)10-4-16(27)20(29)17(28)5-10)21(31-18(12)7-11)9-1-2-13(24)15(26)3-9/h1-7,19,21,23-29H,8H2/t19-,21-/m1/s1

InChi Key：LSHVYAFMTMFKBA-TZIWHRDSSA-N

Canonical SMILES：C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O

Isomeric SMILES：C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O

WGK Germany：3

RTECS：DH9030000

关联CAS：1257-08-5

PubChem CID：107905

MeSH Entry Terms：epicatechin gallate;epicatechin gallate, (2R-cis)-isomer;epicatechin-3-gallate;epicatechin-3-galloyl ester;epicatechin-3-O-gallate

溶解性：Soluble in water (5 mg/ml) with heat and sonication as needed, yielding a clear, colorless solution, ethanol (~1 mg/ml), methanol (sparingly), DMSO (~10 mg/ml), and DMF (~14 mg/ml).

密度：1.8

敏感性：对热敏感

比旋光度：-177° (C=1,EtOH)

熔点：255°C(lit.)

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

个人防护装备：Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

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