产品名称

英文名称：Plerixafor

同义词

Plerixafor、110078-46-1、Mozobil、AMD3100、1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene、Amd 3100、bicyclam JM-2987、SDZ SID 791、Plerixafor hydrochloride、plerixafor (amd3100)、AMD-3100、JM3100、plerixaforum、JKL 169、JM 3100、1-[[4-(1,4,8,11-tetrazacy、普乐沙福、1,4-双[(1,4,8,11-四氮杂环十四烷-1-基)甲基]苯、AMD 3100

产品性质

CAS编号：110078-46-1

分子式：C28H54N8

分子量：502.78

MDL号：MFCD05662218

PubChem编号：65015

别名：普乐沙福|1,4-双[(1,4,8,11-四氮杂环十四烷-1-基)甲基]苯|AMD 3100

英文别名：Plerixafor|110078-46-1|Mozobil|AMD3100|1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene|Amd 3100|bicyclam JM-2987|SDZ SID 791|Plerixafor hydrochloride|plerixafor (amd3100)|AMD-3100|JM3100|plerixaforum|JKL 169|JM 3100|1-[[4-(1,4,8,11-tetrazacy

规格或纯度：≥98%

英文名称：Plerixafor

生化机理：Plerixafor is a stem cell activator, and CXCR4 chemokine antagonis, Drμg treatment of myeloma.

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

产品介绍：Plerixafor is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively. IC50 value 44 nM (CXCR4); 5.7 nM (CXCL12-mediated chemotaxis) Target CXCR4Plerixafor is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively. IC50 value 44 nM (CXCR4); 5.7 nM (CXCL12-mediated chemotaxis) Target CXCR4

PubChem SID：488183652

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488183652

IUPAC Name：1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane

INCHI：InChI=1S/C28H54N8/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36/h5-8,29-34H,1-4,9-26H2

InChi Key：YIQPUIGJQJDJOS-UHFFFAOYSA-N

Canonical SMILES：C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3

Isomeric SMILES：C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3

PubChem CID：65015

Wikipedia：Plerixafor

ChEMBL Ligand：CHEMBL18442

DrugBank Ligand：DB06809

BindingDB Ligand：50035696

CAS Registry No.：110078-46-1

DrugCentral Ligand：4410

GPCRdb Ligand：plerixafor

溶解性：DMSO <1 mg/mL Water 6 mg/mL Ethanol 100 mg/mL

敏感性：对空气、湿度、热敏感

熔点：133 °C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritation

预防措施声明：P305+P351+P338,P280,P302+P352,P321,P264,P362+P364,P264+P265,P337+P317,P332+P317

产品包装