产品名称

英文名称：Sitagliptin phosphate monohydrate

同义词

Sitagliptin phosphate monohydrate、654671-77-9、Januvia、Sitagliptin phosphate hydrate、Glactiv、(R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one phosphate hydrate、Sitagliptin monohydra、磷酸西他列汀一水合物

产品性质

CAS编号：654671-77-9

分子式：C16H15F6N5O.H3PO4.H2O

分子量：523.32

PubChem编号：11591741

别名：磷酸西他列汀一水合物

英文别名：Sitagliptin phosphate monohydrate|654671-77-9|Januvia|Sitagliptin phosphate hydrate|Glactiv|(R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one phosphate hydrate|Sitagliptin monohydra

规格或纯度：≥98%

英文名称：Sitagliptin phosphate monohydrate

应用：A potent, active inhibitor of DPP-IV

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：50mg/100mg/500mg卖完停产，不再备货

产品介绍：Sitagliptin(MK 0431)是DPP4高效抑制剂，在Caco-2细胞中IC50值为19nM。A potent, active inhibitor of DPP-IVSitagliptin phosphate monohydrate is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.A potent, active inhibitor of DPP-IV

PubChem SID：488197608

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488197608

IUPAC Name：(3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;phosphoric acid;hydrate

INCHI：InChI=1S/C16H15F6N5O.H3O4P.H2O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22;1-5(2,3)4;/h4,6,9H,1-3,5,7,23H2;(H3,1,2,3,4);1H2/t9-;;/m1../s1

InChi Key：GQPYTJVDPQTBQC-KLQYNRQASA-N

Canonical SMILES：C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)CC(CC3=CC(=C(C=C3F)F)F)N.O.OP(=O)(O)O

Isomeric SMILES：C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.O.OP(=O)(O)O

PubChem CID：11591741

溶解性：DMSO 100 mg/mL Water 41 mg/mL Ethanol <1 mg/mL

象形图：

信号词：Warning

危险声明：H319 Causes serious eye irritation

预防措施声明：P305+P351+P338,P280,P264+P265,P337+P317

产品包装