产品名称

英文名称：Adriamycin

同义词

doxorubicin、Adriamycin、23214-92-8、Adriablastin、Doxil、Doxorubicine、Doxorubicinum、Adriblastina、14-Hydroxydaunomycin、Hydroxydaunorubicin、Doxorubicina、14-Hydroxydaunorubicine、Adriamycin semiquinone、Doxorubicine [INN-French]、Doxorubicinum [INN-Latin]、Doxorubic、羟基柔红霉素、多柔比星

产品性质

CAS编号：23214-92-8

分子式：C27H29NO11

分子量：543.5

PubChem编号：31703

别名：羟基柔红霉素|多柔比星

英文别名：doxorubicin|Adriamycin|23214-92-8|Adriablastin|Doxil|Doxorubicine|Doxorubicinum|Adriblastina|14-Hydroxydaunomycin|Hydroxydaunorubicin|Doxorubicina|14-Hydroxydaunorubicine|Adriamycin semiquinone|Doxorubicine [INN-French]|Doxorubicinum [INN-Latin]|Doxorubic

规格或纯度：97%

英文名称：Adriamycin

储存温度：2-8°C储存

运输条件：冰袋运输

产品介绍：Adriamycin为抗生素，能抑制DNA拓扑异构酶II，诱导DNA损伤和凋亡。Adriamycin is a Topoisomerase II catalytic inhibitor, also is a broad spectrum antibiotic used in the treatment of cancers.

IUPAC Name：(7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione

INCHI：InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1

InChi Key：AOJJSUZBOXZQNB-TZSSRYMLSA-N

Canonical SMILES：CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)O

Isomeric SMILES：C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)O

PubChem CID：31703

DrugBank Ligand：DB00997

CAS Registry No.：23214-92-8

ChEMBL Ligand：CHEMBL53463

Wikipedia：Doxorubicin

ChEBI：CHEBI28748

RCSB PDB Ligand：DM2

PEP：doxorubicin

Immunopaedia Search：doxorubicin

DrugCentral Ligand：960

溶解性：≥27.2 mg/mL in DMSO; insoluble in EtOH; ≥24.8 mg/mL in H2O with ultrasonic

敏感性：对光线、热敏感

象形图：

信号词：Danger

危险声明：H302 Harmful if swallowedH350 May cause cancer

预防措施声明：P280,P405,P501,P264,P270,P330,P203,P301+P317,P318

产品包装