产品名称

英文名称：BF-170 hydrochloride

同义词

22191-97-5、4-quinolin-2-ylaniline、Benzenamine, 4-(2-quinolinyl)-、4-(Quinolin-2-yl)aniline、2-(4-Aminophenyl)quinoline、(4-Quinolin-2-ylphenyl)amine、NSC168387、Paraaminophenylchinolin、2-(4-Amino)phenylquinoline、SCHEMBL1298412、CHEMBL1411717、AKOS004118002、NSC-1

产品性质

CAS编号：22191-97-5

分子式：C15H12N2 · HCl

分子量：256.73

PubChem编号：297284

英文别名：22191-97-5|4-quinolin-2-ylaniline|Benzenamine, 4-(2-quinolinyl)-|4-(Quinolin-2-yl)aniline|2-(4-Aminophenyl)quinoline|(4-Quinolin-2-ylphenyl)amine|NSC168387|Paraaminophenylchinolin|2-(4-Amino)phenylquinoline|SCHEMBL1298412|CHEMBL1411717|AKOS004118002|NSC-1

规格或纯度：98% (HPLC)

英文名称：BF-170 hydrochloride

生化机理：BF-170 is a new probe for neurofibrillary tangles (tau fibrils). It exhibits greater binding affinity to tau than to Aβ fibrils, EC50 = 221 nM vs. EC50 = 786 nM (Ki for Aβ > 5,000 nM). BF-170 demonstrates fast clearance from the brain; clearly visualizes neurofibrillary tangles, neuropil threads, and paired helical filament-type neuritis. BF-70 may become one of the candidate compounds for in vivo imaging of tau pathology associated with Alzheimer′s disease and is a useful tool in distinguishing among tau and Aβ fibrils specifically in AD.

储存温度：避光,-20°C储存,充氩

运输条件：超低温冰袋运输

IUPAC Name：4-quinolin-2-ylaniline

INCHI：InChI=1S/C15H12N2/c16-13-8-5-12(6-9-13)15-10-7-11-3-1-2-4-14(11)17-15/h1-10H,16H2

InChi Key：PWLMSCCFNGGPGM-UHFFFAOYSA-N

Canonical SMILES：C1=CC=C2C(=C1)C=CC(=N2)C3=CC=C(C=C3)N

Isomeric SMILES：C1=CC=C2C(=C1)C=CC(=N2)C3=CC=C(C=C3)N

WGK Germany：3

PubChem CID：297284

敏感性：对光线敏感

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH335 May cause respiratory irritationH302 Harmful if swallowedH318 Causes serious eye damage

预防措施声明：P261,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P330,P264+P265,P301+P317,P305+P354+P338,P317,P332+P317,P319

个人防护装备：dust mask type N95 (US)， Eyeshields， Faceshields， Gloves

产品包装