产品名称

英文名称：bedaquiline

同义词

Bedaquiline、843663-66-1、TMC207、TMC-207、R207910、TMC 207、AIDS-222089、bedaquilina、bedaquilinum、CHEBI72292、HSDB 8217、Bedaquiline [USANINN]、UNII-78846I289Y、R 207910、R-207910、(1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-p

产品性质

CAS编号：843663-66-1

分子式：C32H31BrN2O2

分子量：555.516

PubChem编号：5388906

英文别名：Bedaquiline|843663-66-1|TMC207|TMC-207|R207910|TMC 207|AIDS-222089|bedaquilina|bedaquilinum|CHEBI72292|HSDB 8217|Bedaquiline [USANINN]|UNII-78846I289Y|R 207910|R-207910|(1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-p

规格或纯度：97%

英文名称：bedaquiline

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：product descriptionBedaquiline (TMC-207, R207910), a diarylquinoline, binds to subunit c of mycobacterial ATP synthase and inhibits its activity. It is highly selective for mycobacterial ATP synthase enzyme compared to homologous eukaryotic enzyme (Selectivity Index >20 000).

IUPAC Name：(1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol

INCHI：InChI=1S/C32H31BrN2O2/c1-35(2)19-18-32(36,28-15-9-13-22-10-7-8-14-26(22)28)30(23-11-5-4-6-12-23)27-21-24-20-25(33)16-17-29(24)34-31(27)37-3/h4-17,20-21,30,36H,18-19H2,1-3H3/t30-,32-/m1/s1

InChi Key：QUIJNHUBAXPXFS-XLJNKUFUSA-N

Canonical SMILES：CN(C)CCC(C1=CC=CC2=CC=CC=C21)(C(C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O

Isomeric SMILES：CN(C)CC[C@@](C1=CC=CC2=CC=CC=C21)([C@H](C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O

PubChem CID：5388906

敏感性：光线敏感

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowedH373 Causes damage to organs through prolonged or repeated exposureH400 Very toxic to aquatic lifeH410 Very toxic to aquatic life with long lasting effects

预防措施声明：P273,P321,P405,P501,P264,P260,P270,P391,P330,P301+P316,P319

产品包装